ITGAL Antikörper

Produktnummer ABIN1837566

Dieses Anti-ITGAL-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von ITGAL in FACS, IHC und IHC (fro). Geeignet für Maus.

Kurzübersicht für ITGAL Antikörper (ABIN1837566)

Target: ITGAL (Integrin alpha-L (ITGAL))

Reaktivität: Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ITGAL Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: 87-6F9

Produktdetails anti-ITGAL Antikörper

Spezifität: CD11a is expressed on lymphocytes, granulocytes, monocytes and macrophages with increase in levels on memory T cells. CD11a or LFA-1 has a key role in mediating leukocyte adhesion to endothelium during inflammatory responses through binding to ICAM-1 (CD54). Other ligands are ICAM-2 and ICAM-3. It is also involved in many T cell functions and immune phenomena. Mol. weight in SDS gels is about 180 kD. Part of heterodimer with CD18 (integrin 9-2). A defect in 9-2 expression results in leucocytes adhesion deficiency (LAD) in which patients suffer from recurring bacterial infections.

Aufreinigung: Purified

Immunogen:

Type of Immunogen: Native protein

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Target Species of Antibody: Mouse

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS, 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 4°C.

Details zu ITGAL

Target: ITGAL (Integrin alpha-L (ITGAL))

Andere Bezeichnung: LFA-1 / CD11A

Hintergrund: Name/Gene ID: ITGAL
Family: Integrin

Synonyms: ITGAL, CD11A, Integrin alpha-L, LFA-1 alpha, LFA-1A, Integrin gene promoter, Alpha polypeptide), CD11a antigen, LFA-1, LFA1A

Gen-ID: 3683

UniProt: P20701

Pathways: Activated T Cell Proliferation, Integrin Complex