Sialoadhesin/CD169 Antikörper (FITC)

Produktnummer ABIN1820283

Dieses Anti-Sialoadhesin/CD169-Antikörper ist ein Ratte Monoklonal-Antikörper zur Detektion von Sialoadhesin/CD169 in FACS und IF. Geeignet für Maus.

Kurzübersicht für Sialoadhesin/CD169 Antikörper (FITC) (ABIN1820283)

Target: Sialoadhesin/CD169 (SIGLEC1) (Sialic Acid Binding Ig-Like Lectin 1, Sialoadhesin (SIGLEC1))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser Sialoadhesin/CD169 Antikörper ist konjugiert mit FITC

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF)

Klon: MOMA-1

Produktdetails anti-Sialoadhesin/CD169 Antikörper (FITC)

Spezifität: Specific for CD169, also known as sialoadhesin. The antibody reacts with a subpopulation of mature resident tissue macrophages. No reactivity is seen with dendritic cells, peritoneal resident macrophages, peritoneal exudate cells or blood cells. Distinct macrophage subpopulations of lymphoid organs express the antigen. In the spleen, they are localized at the marginal sinus forming a ring around the periarteriolar lymphocyte sheath and follicular areas at the inner side of marginal zones. In lymph nodes, they are localized in the sinusoids and medullary cords but not within follicular areas or paracortex. In Peyer's patches they are localized in the interfollicular areas at the serosal side. Kupffer cells in the liver can be clearly stained by MOMA-1, although antigen expression is weaker than that seen in splenic macrophages. No MOMA-1 positive macrophages were found in the thymus. Reactivity was also negative in following organs tested so far (kidney, brain, skin). In non-lymphoid organs, the antigen is only found on a macrophage subpopulation in the lamina propria of the villi of the small intestine.

Keine Kreuzreaktivität: Human, Ratte (Rattus)

Aufreinigung: Protein G purified

Immunogen: Stromal (reticular) elements from spleen.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Approved: Flo (1:1), IF

Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Kommentare:

Target Species of Antibody: Mouse

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS, 0.09 % sodium azide, 1 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing. Protect from light.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short term: store at 4°C. Long term: -20°C. Avoid freeze-thaw cycles. Protect from light.

Details zu Sialoadhesin/CD169

Target: Sialoadhesin/CD169 (SIGLEC1) (Sialic Acid Binding Ig-Like Lectin 1, Sialoadhesin (SIGLEC1))

Andere Bezeichnung: SIGLEC1 / CD169 / Sialoadhesin

Hintergrund: Name/Gene ID: SIGLEC1
Family: Immunoglobulin

Synonyms: SIGLEC1, CD169, CD169 antigen, SIGLEC-1, Sialoadhesin, SN, DJ1009E24.1

Gen-ID: 6614