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CD276 Antikörper (AA 1-242)

CD276 Reaktivität: Maus FACS Wirt: Ratte Monoclonal MJ18 unconjugated

Produktnummer ABIN1820150

Datenblatt (PDF)

Target Alle CD276 Antikörper anzeigen

CD276
Bindungsspezifität
15

7

5

4

4

3

3

3

3

2

2

1

1

1

1

1

1

1

1

1

1

1

1
AA 1-242
Reaktivität
68

40

10

5

5

3

2

2

1
Maus
Wirt
49

19

11

1
Ratte
Passende Sekundärantikörper
Klonalität
44

35

1
Monoklonal
Konjugat
44

6

6

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser CD276 Antikörper ist unkonjugiert
Applikation
47

26

24

14

13

11

9

8

8

5

3

3

2

2

1

1
Flow Cytometry (FACS)

Spezifität

Recognizes mouse CD276, otherwise known as B7-H3, a ubiquitously expressed transmembrane glycoprotein and member of the B7 family of co-stimulatory molecules, which acts as both a positive and negative regulator of T-cell-mediated immune responses. CD276 is highly expressed in bone during embryogenesis, and can be induced on dendritic cells and monocytes by inflammatory cytokines. CD276 has been implicated in the development of acute and chronic transplant rejection, and is reported to have therapeutic potential as a regulator of cell-mediated immune responses to cancer, particularly in conjunction with anti-angiogenic therapy. In mice, CD276 has been linked with the development of pathogenic Th2 cells during the induction phase of allergic asthma. Studies have shown that clone MJ18 inhibits stimulated CD4+ T-cell proliferation.

Aufreinigung

Protein G purified

Immunogen

Mouse IgG2a Fc-CD276 (aa 1-242).

Type of Immunogen: Fusion protein

Klon

MJ18

Isotyp

IgG1

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CD276 Reaktivität: Human ELISA, FACS, IHC Wirt: Maus Monoclonal 6A1 unconjugated

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CD276 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated

anti-CD276 (CD276) (AA 47-219) antibody
CD276 Reaktivität: Human WB, IHC, IP, ICC Wirt: Maus Monoclonal C2 unconjugated

anti-CD276 (CD276) (AA 29-200) antibody
CD276 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated

anti-CD276 (CD276) (AA 101-200) antibody
CD276 Reaktivität: Human, Maus WB, ELISA, ICC, IHC (p), IF (p), IF (cc), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

Approved: Flo (1:25 - 1:200)

Kommentare

Target Species of Antibody: Mouse

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

Lot specific

Buffer

PBS, 0.09 % sodium azide

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung

Avoid repeated freezing and thawing.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

4°C or -20°C, Avoid freeze-thaw cycles.
Target

CD276

Andere Bezeichnung

CD276 / B7-H3 (CD276 Produkte)

Hintergrund

Name/Gene ID: CD276

Synonyms: CD276, 4Ig-B7-H3, B7 homolog 3, B7-H3, CD276 antigen, CD276 Molecule, Costimulatory molecule, B7H3, B7RP-2

Gen-ID

80381

UniProt

Q5ZPR3

Pathways

Cancer Immune Checkpoints