Nitrotyrosine Antikörper
Kurzübersicht für Nitrotyrosine Antikörper (ABIN1820112)
Target
Alle Nitrotyrosine Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- Recognizes both free and protein-bound nitrotyrosine (Tyr-NO2), including human serum nitro albumin, nitro insulin and nitro haemoglobin. Nitrotyrosine arises from the nitration of protein tyrosine residues, by reactive nitrogen species such as peroxynitrite and nitrogen dioxide, and can be used as a measure of NO-dependent oxidative stress and cell damage. Increased levels of nitrotyrosine are detectable in various pathological conditions including atherosclerosis, rheumatoid arthritis, cardiovascular disease, lung cancer and vasculitis. The specificity of the antibody as determined by competition ELISA is: Nitrotyrosine:95 % of inhibition, Tyrosine:0 % of inhibition, Nitrotryptophan:4 % of inhibition, Aminotyrosine:0 % of inhibition, Phosphotyrosine:2 % of inhibition, Chlorotyrosine:3 % of inhibition,.
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Aufreinigung
- Protein A purified
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Immunogen
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Protein-bound Nitrotyrosine.
Type of Immunogen: Hapten -
Isotyp
- IgG1
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Applikationshinweise
- Approved: ELISA, IP (1 μg/mL), WB (0.1 μg/mL)
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- PBS, 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- 4°C or -20°C, Avoid freeze-thaw cycles.
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- Nitrotyrosine
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Substanzklasse
- Chemical
Target
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