CD276 Antikörper (AA 1-242) (PE)
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- Target Alle CD276 Antikörper anzeigen
- CD276
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Bindungsspezifität
- AA 1-242
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Reaktivität
- Maus
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Wirt
- Ratte
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD276 Antikörper ist konjugiert mit PE
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Applikation
- Flow Cytometry (FACS)
- Spezifität
- Recognizes mouse CD276, otherwise known as B7-H3, a ubiquitously expressed transmembrane glycoprotein and member of the B7 family of co-stimulatory molecules, which acts as both a positive and negative regulator of T-cell-mediated immune responses. CD276 is highly expressed in bone during embryogenesis, and can be induced on dendritic cells and monocytes by inflammatory cytokines. CD276 has been implicated in the development of acute and chronic transplant rejection, and is reported to have therapeutic potential as a regulator of cell-mediated immune responses to cancer, particularly in conjunction with anti-angiogenic therapy. In mice, CD276 has been linked with the development of pathogenic Th2 cells during the induction phase of allergic asthma, see for details.
- Aufreinigung
- Protein G purified
- Immunogen
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Mouse IgG2a Fc-CD276 (aa 1-242).
Type of Immunogen: Fusion protein - Klon
- MJ8
- Isotyp
- IgG2b
- Top Product
- Discover our top product CD276 Primärantikörper
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- Applikationshinweise
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Approved: Flo
Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. - Kommentare
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Target Species of Antibody: Mouse
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Rekonstitution
- Distilled water
- Konzentration
- Lot specific
- Buffer
- PBS, 0.09 % sodium azide, 1 % BSA, 5 % sucrose
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Do not freeze. Protect from light.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store at 4°C. Do not freeze. Protect from light.
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- Target
- CD276
- Andere Bezeichnung
- CD276 / B7-H3 (CD276 Produkte)
- Hintergrund
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Name/Gene ID: CD276
Synonyms: CD276, 4Ig-B7-H3, B7 homolog 3, B7-H3, CD276 antigen, CD276 Molecule, Costimulatory molecule, B7H3, B7RP-2 - Gen-ID
- 80381
- UniProt
- Q5ZPR3
- Pathways
- Cancer Immune Checkpoints
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