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CD276 Antikörper (AA 1-242) (PE)

CD276 Reaktivität: Maus FACS Wirt: Ratte Monoclonal MJ8 PE
Produktnummer ABIN1819131
  • Target Alle CD276 Antikörper anzeigen
    CD276
    Bindungsspezifität
    • 15
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-242
    Reaktivität
    • 66
    • 37
    • 9
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    Maus
    Wirt
    • 48
    • 18
    • 9
    • 1
    Ratte
    Klonalität
    • 43
    • 32
    • 1
    Monoklonal
    Konjugat
    • 41
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD276 Antikörper ist konjugiert mit PE
    Applikation
    • 46
    • 23
    • 23
    • 14
    • 13
    • 11
    • 8
    • 8
    • 8
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Flow Cytometry (FACS)
    Spezifität
    Recognizes mouse CD276, otherwise known as B7-H3, a ubiquitously expressed transmembrane glycoprotein and member of the B7 family of co-stimulatory molecules, which acts as both a positive and negative regulator of T-cell-mediated immune responses. CD276 is highly expressed in bone during embryogenesis, and can be induced on dendritic cells and monocytes by inflammatory cytokines. CD276 has been implicated in the development of acute and chronic transplant rejection, and is reported to have therapeutic potential as a regulator of cell-mediated immune responses to cancer, particularly in conjunction with anti-angiogenic therapy. In mice, CD276 has been linked with the development of pathogenic Th2 cells during the induction phase of allergic asthma, see for details.
    Aufreinigung
    Protein G purified
    Immunogen
    Mouse IgG2a Fc-CD276 (aa 1-242).

    Type of Immunogen: Fusion protein
    Klon
    MJ8
    Isotyp
    IgG2b
    Top Product
    Discover our top product CD276 Primärantikörper
  • Applikationshinweise
    Approved: Flo

    Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
    Kommentare

    Target Species of Antibody: Mouse

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Rekonstitution
    Distilled water
    Konzentration
    Lot specific
    Buffer
    PBS, 0.09 % sodium azide, 1 % BSA, 5 % sucrose
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Do not freeze. Protect from light.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 4°C. Do not freeze. Protect from light.
  • Target
    CD276
    Andere Bezeichnung
    CD276 / B7-H3 (CD276 Produkte)
    Hintergrund
    Name/Gene ID: CD276

    Synonyms: CD276, 4Ig-B7-H3, B7 homolog 3, B7-H3, CD276 antigen, CD276 Molecule, Costimulatory molecule, B7H3, B7RP-2
    Gen-ID
    80381
    UniProt
    Q5ZPR3
    Pathways
    Cancer Immune Checkpoints
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