CMA1 Antikörper

Produktnummer ABIN181829

Der Maus Monoklonal Anti-CMA1-Antikörper wurde für WB, IHC (p), EIA und IHC (fro) validiert. Er ist geeignet, CMA1 in Proben von Human zu detektieren.

Kurzübersicht für CMA1 Antikörper (ABIN181829)

Target: CMA1 (Chymase 1, Mast Cell (CMA1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CMA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: CC1

Produktdetails anti-CMA1 Antikörper

Spezifität: This antibody binds to mast cell chymase, it may be used to detect mast cells in routinely fixed tissues, and has been used to study the distribution of mast cells in skin, synovium, lung and heart. Binding of this antibody to chymase is not reduced in the presence of heparin, suggesting that the antibody does not bind to the heparin-binding domain of chymase.

Aufreinigung: Affinity Chromatography on Protein G.

Immunogen: Purified human skin chymase. Spleen cells from immunised BALB/c mice were fused with cells of the P3/NSI/I.Ag4.1 mouse myeloma cell line.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot. Immunohistochemistry on frozen sections: 1/500 - 1/1000, This product does not require protein digestion pre-treatment of paraffin sections. This product does not require antigen retrieval using heat treatment prior to staining of paraffin sections. Recommended Positive Control: Skin
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu CMA1

Target: CMA1 (Chymase 1, Mast Cell (CMA1))

Andere Bezeichnung: Mast Cell Chymase

Hintergrund: Mast Cell Chymase is an important marker of mast cells and also an important mediator of inflammation.Synonyms: Alpha-chymase, CMA1, CYH, CYM, Mast cell protease I

Gen-ID: 1215

NCBI Accession: NP_001827

UniProt: P23946

Pathways: ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Carbohydrate Homeostasis