EGFR Antikörper (Extracellular Domain) (PE)
Kurzübersicht für EGFR Antikörper (Extracellular Domain) (PE) (ABIN181809)
Target
Alle EGFR Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Bindungsspezifität
- Extracellular Domain
-
Spezifität
- This antibody recognises the epidermal growth factor receptor (EGFR). This antibody binds to epitope B from EGFR (1, 2).Aff. Const.:6.7 x 10e-9 M
-
Aufreinigung
- Affinity chromatography on Protein G
-
Immunogen
- Extracellular domain of human EGF-receptor from head and neck carcinoma.
-
Isotyp
- IgG2a
-
-
anti-Epidermal Growth Factor Receptor (EGFR) (AA 693-893) antibody
EGFR Reaktivität: Human WB, ELISA, IHC, FACS Wirt: Maus Monoclonal 7A6F12 unconjugated
anti-Epidermal Growth Factor Receptor (EGFR) (AA 888-1210) antibodyEGFR Reaktivität: Human WB, IHC Wirt: Maus Monoclonal C4 unconjugated
anti-Epidermal Growth Factor Receptor (EGFR) (AA 1021-1210) antibodyEGFR Reaktivität: Human WB, IF, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Epidermal Growth Factor Receptor (EGFR) (AA 1163-1191), (C-Term) antibodyEGFR Reaktivität: Human WB, IHC (p) Wirt: Maus Monoclonal 688CT33-1-3 unconjugated
anti-Epidermal Growth Factor Receptor (EGFR) (C-Term) antibodyEGFR Reaktivität: Human, Maus, Ratte, Schwein, Affe, Rind (Kuh), Huhn, Hund, Pferd, Kaninchen, Meerschweinchen, Avian, Cat, Esel, Ziege, Hamster, Schaf WB Wirt: Ziege Polyclonal unconjugated
anti-Epidermal Growth Factor Receptor (EGFR) (AA 693-893) antibodyEGFR Reaktivität: Human WB, ELISA, FACS Wirt: Maus Monoclonal 5E10D3 unconjugated
anti-Epidermal Growth Factor Receptor (EGFR) (pSer1071) antibodyEGFR Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Epidermal Growth Factor Receptor (EGFR) (pSer695) antibodyEGFR Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Epidermal Growth Factor Receptor (EGFR) (pSer1026) antibodyEGFR Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Epidermal Growth Factor Receptor (EGFR) (C-Term) antibodyEGFR Reaktivität: Human, Ratte WB, ELISA, IHC, IP Wirt: Kaninchen Polyclonal unconjugated
-
-
Applikationshinweise
-
Flow Cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Rekonstitution
- Restore with 1.0 mL distilled water
-
Buffer
- PBS containing 1 % BSA and 5 % Bovine Serum Albumin
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- Use of sodium azide as a preservative will substantially inhibit the enzyme activity of horseradish peroxidase.
-
Handhabung
- Avoid repeated freezing and thawing.
-
Lagerung
- 4 °C/-20 °C
-
Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
- EGFR (Epidermal Growth Factor Receptor (EGFR))
-
Andere Bezeichnung
- EGFR / ERBB1
-
Hintergrund
- EGFR is over expressed in a high proportion of breast cancer cells and in a range of other carcinomas. High level expression of EGFR is often associated with advanced disease and poor prognosis.Synonyms: EGF Receptor, Epidermal growth factor receptor, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1, c-ErbB-1, erbB-1
-
Gen-ID
- 1956
-
NCBI Accession
- NP_005219
-
UniProt
- P00533
-
Pathways
- NF-kappaB Signalweg, RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteine
Target
-
