EGFR Antikörper (Extracellular Domain) (PE)
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- Target Alle EGFR Antikörper anzeigen
- EGFR (Epidermal Growth Factor Receptor (EGFR))
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Bindungsspezifität
- Extracellular Domain
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Reaktivität
- Human
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Wirt
- Ratte
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Klonalität
- Monoklonal
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Konjugat
- Dieser EGFR Antikörper ist konjugiert mit PE
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Applikation
- Flow Cytometry (FACS)
- Spezifität
- This antibody recognises the epidermal growth factor receptor (EGFR). This antibody binds to epitope B from EGFR (1, 2).Aff. Const.:6.7 x 10e-9 M
- Aufreinigung
- Affinity chromatography on Protein G
- Immunogen
- Extracellular domain of human EGF-receptor from head and neck carcinoma.
- Klon
- ICR10
- Isotyp
- IgG2a
- Top Product
- Discover our top product EGFR Primärantikörper
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- Applikationshinweise
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Flow Cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Rekonstitution
- Restore with 1.0 mL distilled water
- Buffer
- PBS containing 1 % BSA and 5 % Bovine Serum Albumin
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- Use of sodium azide as a preservative will substantially inhibit the enzyme activity of horseradish peroxidase.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- EGFR (Epidermal Growth Factor Receptor (EGFR))
- Andere Bezeichnung
- EGFR / ERBB1 (EGFR Produkte)
- Hintergrund
- EGFR is over expressed in a high proportion of breast cancer cells and in a range of other carcinomas. High level expression of EGFR is often associated with advanced disease and poor prognosis.Synonyms: EGF Receptor, Epidermal growth factor receptor, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1, c-ErbB-1, erbB-1
- Gen-ID
- 1956
- NCBI Accession
- NP_005219
- UniProt
- P00533
- Pathways
- NF-kappaB Signalweg, RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteine
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