Galectin 3 Antikörper (Biotin)

Produktnummer ABIN181681

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Galectin 3 in WB und EIA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Galectin 3 Antikörper (Biotin) (ABIN181681)

Target: Galectin 3 (LGALS3)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Galectin 3 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-Galectin 3 Antikörper (Biotin)

Aufreinigung: Affinity Chromatography.

Immunogen: Highly pure (> 98%) recombinant human Galectin-3

Anwendungsinformationen

Applikationshinweise: ELISADirect: To detect hGalectin-3 (using 100 μL/well antibody solution) a concentration ofapprox. 1.0 μg/mL of this antibody is required. In conjunction with compatible secondaryreagents, allows the detection of at least 0.2-0.4 ng/well of recombinant HumanGalectin-3. Sandwich: To detect Human Galectin-3 (using 100 μL/well antibody solution) aconcentration of 0.25-1.0 μg/mL of this antibody is required. In conjunction with PolyclonalAnti-Human Galectin-3 (ABIN181683 or ABIN181684) as a capture antibody, it allows thedetection of at least 0.2-0.4 ng/well of recombinant Human Galectin-3. Western blot

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore in sterile PBS containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL.

Buffer: PBS, pH 7.2 without preservatives.

Konservierungsmittel: Without preservative

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the lyophilized antibody at -20 °C. Following reconstitution it is stable for two weeks at 2-8 °C. Frozen aliquots are stable for 6 months when stored at -20 °C.

Haltbarkeit: 6 months

Details zu Galectin 3

Target: Galectin 3 (LGALS3)

Andere Bezeichnung: Galectin-3

Substanzklasse: Chemical

Hintergrund: Lectins, of either plant or animal origin, are carbohydrate binding proteins that interact with glycoprotein and glycolipids on the surface of animal cells. The Galectins are lectins that recognize and interact with beta-galactoside moieties. Galectin-3 regulates a number of biological processes, including embryogenesis, inflammatory responses, cell progression and metastasis. Galectin-3 is normally expressed in epithelia of a variety of tissues, including colon and endometrium, and in various inflammatory cells, including macrophages. Galectin-3 can function intracellularly, in controlling cell cycle and preventing T-cell apoptosis, and also extracellularly, in activating various cells, including monocytes/macrophages, mast cells, neutrophils, and lymphocytes. Expression of Galectin-3 is affected by neoplastic transformation, being up-regulated in certain types of lymphomas, and in thyroid and hepatic carcinomas. Conversely, it is down-regulated in other cancers, such as colon, breast, ovarian, and uterine.Synonyms: 35 kDa lectin, CBP35, Carbohydrate-binding protein 35, GAL3, GALBP, Galactose-specific lectin 3, IgE-binding protein, L-31, L-34 galactoside-binding lectin, Laminin-binding protein, Lectin L-29, Lgals3, Mac-2

Gen-ID: 9606

UniProt: P17931

Pathways: RTK Signalweg