EPH Receptor A4 Antikörper (C-Term)

Produktnummer ABIN181176

Der Kaninchen Polyklonal anti-EPH Receptor A4 Antikörper (ABIN181176) detektiert spezifisch EPH Receptor A4 in IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für EPH Receptor A4 Antikörper (C-Term) (ABIN181176)

Target: EPH Receptor A4 (EPHA4)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EPH Receptor A4 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-EPH Receptor A4 Antikörper

Bindungsspezifität: C-Term

Spezifität: This antibody detects Ephrin Type A Receptor 4.

Aufreinigung: Immunoaffinity chromatography

Immunogen: EPHA4 antibody was raised against synthetic peptide from C-terminal domain of human EPHA4. Genename: EPHA4

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry: 18 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS containing 0.009 % sodium azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C for longer.

Details zu EPH Receptor A4

Target: EPH Receptor A4 (EPHA4)

Andere Bezeichnung: EPHA4

Hintergrund: Eph receptor A4 is a receptor for members of the ephrin-A family. It binds to ephrin-A1, -A4 and -A5 but binds more poorly to ephrin-A2 and -A3. Eph receptor A4 may play a role in a signal transduction process involved in hindbrain pattern formation. Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).Synonyms: Ephrin type-A receptor 4, HEK8, Receptor protein-tyrosine kinase HEK8, SEK, TYRO1, Tyrosine-protein kinase TYRO1, Tyrosine-protein kinase receptor SEK

Gen-ID: 2043

NCBI Accession: NP_004429

UniProt: P54764

Pathways: RTK Signalweg