CD79a Antikörper (AA 202-216)

Produktnummer ABIN181100

Der Maus Monoklonal Anti-CD79a Antikörper wurde für FACS, WB, IHC (p) und IHC (fro) validiert. Er ist geeignet, CD79a in Proben von Human, Maus, Ratte, Rind (Kuh), Schwein, Affe, Huhn, Kaninchen, Pferd, Meerschweinchen und Hund zu detektieren.

Kurzübersicht für CD79a Antikörper (AA 202-216) (ABIN181100)

Target: CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schwein, Affe, Huhn, Kaninchen, Pferd, Meerschweinchen, Hund

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD79a Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: HM57

Produktdetails anti-CD79a Antikörper

Bindungsspezifität: AA 202-216

Spezifität: This antibody recognizes an epitope within the cytoplasmic domain of CD79a.

Kreuzreaktivität (Details): Species reactivity (tested):Human, American Bison, Fallow Deer, Canine, Monkey, Pig, Horse, Bovine, Guinea Pig, Rat, Mouse, Rabbit, Chicken.

Produktmerkmale: Synonyms: IGA, MB1, B-Cell marker, B-cell antigen receptor complex-associated protein alpha-chain,MB-1 membrane glycoprotein, Surface IgM-associated protein, Membrane-boundimmunoglobulin-associated protein

Aufreinigung: Affinity Chromatography on Protein G

Immunogen: Synthetic peptide corresponding to 202-216 amino acid sequence of human mb-1. Spleencells from immunised Balb/c mice were fused with cells of the Sp2/0 myeloma cell line. Genename: CD79a

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Western Blot. Immunohistochemistry on frozen sections. Immunohistochemistry on paraffin sections: This product requires antigen retrieval usingheat treatment prior to staining of paraffin sections. Sodium citrate buffer pH 6.0 isrecommended for this purpose. Recommended Positive Control: Human tonsilFlow Cytometry: 1/10 - 1/25, use 10 μL of the suggested working dilution to label 1x10^6cells in 100 μL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.1 mg/mL

Buffer: PBS, pH 7.4, 0.09 % Sodium Azide, 1 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu CD79a

Target: CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))

Andere Bezeichnung: CD79a

Hintergrund: CD79a, also known as mb-1, is a 45kD protein that is expressed by B lymphocytes during differentiation from early pre-B cell stage through to plasma cells. The CD79a molecule associates with CD79b (B29) to form a heterodimer that is non-covalently linked to surface immunoglobulin, forming the B-cell receptor (BCR) complex. The CD79a/CD79b heterodimers are also necessary for intracellular signalling following antigen-binding to surface immunoglobulin.Synonyms: B-Cell marker, B-cell antigen receptor complex-associated protein alpha-chain, IGA, MB-1 membrane glycoprotein, MB1, Membrane-bound immunoglobulin-associated protein, Surface IgM-associated protein

Gen-ID: 973

UniProt: P11912

Pathways: BCR Signaling