RAB27A Antikörper (AA 1-221)

Produktnummer ABIN1742354

Der Kaninchen Polyklonal Anti-RAB27A Antikörper wurde für WB, IP und IHC (p) validiert. Er ist geeignet, RAB27A in Proben von Human, Maus und Ratte zu detektieren. Es sind 2+ Publikationen verfügbar.

Kurzübersicht für RAB27A Antikörper (AA 1-221) (ABIN1742354)

Target: RAB27A (RAB27A, Member RAS Oncogene Family (RAB27A))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAB27A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Güteklasse: KO Validated

Produktdetails anti-RAB27A Antikörper

Bindungsspezifität: AA 1-221

Verwendungszweck: Rabbit anti-Rab27A antibody

Spezifität: Specific for rab 27A

Kreuzreaktivität (Details): Reacts with: rat (P23640), mouse (Q9ERI2), human (P51159). Other species not tested yet.

Aufreinigung: affinity purified

Immunogen: Recombinant protein corresponding to AA 1 to 221 from rat Rab27A (UniProt Id: P23640)

Anwendungsinformationen

Applikationshinweise: WB:1 : 1000 , IP:yes ICC:not tested yet IHC:not tested yet IHC-P:1 : 2000,

Kommentare:

Only the non-conserved C-terminal part of the protein was used for affinity purification to achieve specificity.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: For reconstitution add 50 μLH2O to get a 1 mg/mL solution in PBS.

Buffer: PBS. Albumin was added for stabilization.

Handhabung: Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

Lagerung: -20 °C,-80 °C,4 °C

Informationen zur Lagerung: Antibodies should be stored at +4°C when still lyophilized. Then aliquot and store at -20°C to -80°C until use. Albumin was added for stabilization. Do not freeze!

Referenzen für anti-RAB27A Antikörper (ABIN1742354)

Hou, Ernst, Stuenkel, Lentz, Williams: "Rab27A Is Present in Mouse Pancreatic Acinar Cells and Is Required for Digestive Enzyme Secretion." in: PLoS ONE, Vol. 10, Issue 5, pp. e0125596, (2015) (PubMed).

Lovis, Roggli, Laybutt, Gattesco, Yang, Widmann, Abderrahmani, Regazzi: "Alterations in microRNA expression contribute to fatty acid-induced pancreatic beta-cell dysfunction." in: Diabetes, Vol. 57, Issue 10, pp. 2728-36, (2008) (PubMed).

Details zu RAB27A

Target: RAB27A (RAB27A, Member RAS Oncogene Family (RAB27A))

Andere Bezeichnung: Rab27A

Hintergrund:

Synonyms: Rab27, pancreas, insulin granules, secretory vesicles, pancreatic islands

Antigen Information: K.O. Rab27 proteins are members of the Rab family responsible for melanosomal transport and hormone secretion

UniProt: P23640

Pathways: Peptide Hormone Metabolism