ESRRA Antikörper (N-Term)

Produktnummer ABIN1734163

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch ESRRA in WB und ICC. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Hund und Schwein.

Kurzübersicht für ESRRA Antikörper (N-Term) (ABIN1734163)

Target: ESRRA (Estrogen-Related Receptor alpha (ESRRA))

Reaktivität: Human, Maus, Ratte, Hund, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ESRRA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunocytochemistry (ICC)

Produktdetails anti-ESRRA Antikörper

Bindungsspezifität: AA 1-50, N-Term

Spezifität: Reacts with human and mouse ESRRA protein

Kreuzreaktivität (Details): May cross react with rat, pig and dog (100 % sequence homology).

Aufreinigung: Purified

Immunogen: Synthetic peptide made to an N-terminal portion of the human protein (within residues 1-50). [Swiss-Prot# P11474]

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
- ICC : 1/100 - WB : 2.0 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, glycerol 30 % , Sodium azide 0.1 %

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Short term storage at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Haltbarkeit: 6 months

Details zu ESRRA

Target: ESRRA (Estrogen-Related Receptor alpha (ESRRA))

Andere Bezeichnung: Estrogen-Related Receptor alpha (ERR-Alpha)

Hintergrund: Estrogen-related receptor alpha (ERR alpha) is an orphan member of the superfamily of nuclear hormone receptors. It was initially isolated based on its sequence homology to the estrogen receptor but is not activated by classic estrogens. ERR alpha preferentially binds to an ERR alpha response element (ERRE) containing a single consensus half-site, TNAAGGTCA. ERR alpha can control the expression of MCAD through the NRRE-1 and thus may play an important role in regulating cellular energy balance in vivo.

Gen-ID: 2101

UniProt: P11474

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha