Axin Antikörper (C-Term)
Kurzübersicht für Axin Antikörper (C-Term) (ABIN1732156)
Target
Alle Axin (AXIN1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Spezifität
- Reacts with the C-terminus part of human AXIN1
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Kreuzreaktivität
- Maus, Rind (Kuh), Hund, Ratte (Rattus)
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Kreuzreaktivität (Details)
- Cross reacts with bovine, canine, mouse and rat protein. This antibody is expected to recognise both reported isoforms.
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Aufreinigung
- Antigen affinity purified
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Immunogen
- Synthetic peptide C-FEEKIIGKVEKVD from the C-terminus of human AXIN1 (NP_003493.1, NP_851393.1). Percent identity with other species by BLAST analysis: Human (100%), Gorilla (100%), Gibbon (100%), Baboon (100%), Monkey (100%), Marmoset (100%)
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anti-Axin 1 (AXIN1) (AA 546-752) antibody
AXIN1 Reaktivität: Human ELISA, ICC, FACS Wirt: Maus Monoclonal 4E9F1 unconjugated
anti-Axin 1 (AXIN1) (AA 618-827) antibodyAXIN1 Reaktivität: Ratte WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Axin 1 (AXIN1) (AA 643-740) antibodyAXIN1 Reaktivität: Human WB, ELISA, IF, PLA Wirt: Maus Monoclonal 2B11 unconjugated
anti-Axin 1 (AXIN1) (AA 546-752) antibodyAXIN1 Reaktivität: Human ELISA Wirt: Maus Monoclonal 4F10G1 unconjugated
anti-Axin 1 (AXIN1) (AA 653-862) antibodyAXIN1 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Axin 1 (AXIN1) (AA 710-738), (C-Term) antibodyAXIN1 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB31751 unconjugated
anti-Axin 1 (AXIN1) (AA 710-738) antibodyAXIN1 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Axin 1 (AXIN1) (AA 654-863) antibodyAXIN1 Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Axin 1 (AXIN1) (AA 418-707) antibodyAXIN1 Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Axin 1 (AXIN1) (AA 761-862) antibodyAXIN1 Reaktivität: Human, Maus WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
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Working dilution: ELISA (1:128000), IHC-P (3.75 μg/mL)
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Buffer
- TBS, pH 7.3, BSA 0.5 % , Sodium azide 0.02 %
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Minimize freezing and thawing.
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- Axin (AXIN1) (Axin 1 (AXIN1))
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Andere Bezeichnung
- AXIN1
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Hintergrund
- Component of the beta-catenin destruction complex required for regulating CTNNB1 levels through phosphorylation and ubiquitination, and modulating Wnt-signaling. Controls dorsoventral patterning via two opposing effects, down-regulates CTNNB1 to inhibit the Wnt signaling pathway and ventralize embryos, but also dorsalizes embryos by activating a Wnt-independent JNK signaling pathway.
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UniProt
- O15169
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Pathways
- WNT Signalweg, Sensory Perception of Sound, Regulation of G-Protein Coupled Receptor Protein Signaling
Target
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