Axin Antikörper (C-Term)
Kurzübersicht für Axin Antikörper (C-Term) (ABIN1732155)
Target
Alle Axin (AXIN1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Spezifität
- Reacts with human AXIN1
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Aufreinigung
- Antigen affinity purified
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Immunogen
- 14 amino acid peptide near the carboxy terminus of human AXIN1
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Isotyp
- IgG
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Applikationshinweise
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Working dilution: IHC - P (5 μg/mL), WB (1 - 2 μg/mL)
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- PBS, Sodium azide 0.02 %
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
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- Axin (AXIN1) (Axin 1 (AXIN1))
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Andere Bezeichnung
- AXIN1
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Hintergrund
- Component of the beta-catenin destruction complex required for regulating CTNNB1 levels through phosphorylation and ubiquitination, and modulating Wnt-signaling. Controls dorsoventral patterning via two opposing effects, down-regulates CTNNB1 to inhibit the Wnt signaling pathway and ventralize embryos, but also dorsalizes embryos by activating a Wnt-independent JNK signaling pathway.
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UniProt
- O15169
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Pathways
- WNT Signalweg, Sensory Perception of Sound, Regulation of G-Protein Coupled Receptor Protein Signaling
Target
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