ACVR1 Antikörper (N-Term)

Produktnummer ABIN1731497

Produktdetails anti-ACVR1 Antikörper

Target: ACVR1 (ACRV1) (Activin Receptor Type I (ACRV1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ACVR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: Reacts with human ACVR1B

Kreuzreaktivität: Maus, Ratte (Rattus)

Kreuzreaktivität (Details): Cross reacts with mouse and rat protein.

Aufreinigung: Antigen affinity purified

Immunogen: Synthetic 15 amino acid peptide near the amino terminus of the human ACVR1C.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Working dilution: IHC - P (5 μg/mL), WB (1 μg/mL)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, Sodium azide 0.02 %

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.

Details zu ACVR1

Target: ACVR1 (ACRV1) (Activin Receptor Type I (ACRV1))

Andere Bezeichnung: ACVR1 / ALK2 (ACRV1 Produkte)

Hintergrund: On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin. May be involved for left-right pattern formation during embryogenesis

UniProt: Q04771