MEF2A Antikörper (AA 391-497)

Produktnummer ABIN1724919

Produktdetails anti-MEF2A Antikörper

Target: MEF2A (Myocyte Enhancer Factor 2A (MEF2A))

Bindungsspezifität: AA 391-497

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MEF2A Antikörper ist unkonjugiert

Applikation: ELISA

Verwendungszweck: MEF2A Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human MEF2A (AA: 391-497) expressed in E. Coli.

Klon: 2F9H2

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-MEF2A Antikörper (ABIN1724919)

Zhao, Zhao, Peng: "The effects of myocyte enhancer factor 2A gene on the proliferation, migration and phenotype of vascular smooth muscle cells." in: Cell biochemistry and function, Vol. 30, Issue 2, pp. 108-13, (2012) (PubMed).

Guella, Rimoldi, Asselta, Ardissino, Francolini, Martinelli, Girelli, Peyvandi, Tubaro, Merlini, Mannucci, Duga: "Association and functional analyses of MEF2A as a susceptibility gene for premature myocardial infarction and coronary artery disease." in: Circulation. Cardiovascular genetics, Vol. 2, Issue 2, pp. 165-72, (2009) (PubMed).

Details zu MEF2A

Target: MEF2A (Myocyte Enhancer Factor 2A (MEF2A))

Andere Bezeichnung: MEF2A (MEF2A Produkte)

Hintergrund: The protein encoded by this gene is a DNA-binding transcription factor that activates many muscle-specific, growth factor-induced, and stress-induced genes. The encoded protein can act as a homodimer or as a heterodimer and is involved in several cellular processes, including muscle development, neuronal differentiation, cell growth control, and apoptosis. Defects in this gene could be a cause of autosomal dominant coronary artery disease 1 with myocardial infarction (ADCAD1). Several transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 54.8 kDa

UniProt: Q02078

Pathways: Neurotrophin Signalübertragung, Activation of Innate immune Response, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades