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SQSTM1 Antikörper (AA 232-356)

Name: SQSTM1 Antikörper (AA 232-356)
Brand: antibodies-online
SKU: ABIN1724836
Price: 542.24 EUR
Availability: InStock

Dieses Maus Monoklonal-Antikörper erkennt spezifisch SQSTM1 in WB, IHC, ELISA und FACS. Er zeigt eine Reaktivität gegenüber Human und wurde in 1 Publikation erwähnt.

Western blot analysis using SQSTM1 mouse mAb against Hela (1), Jurkat (2), THP-1 (3), HEK293 (4), A549 (5), MCF-7 (6), HepG2 (7), COS7 (8) and SK-BR-3 (9) cell lysate. (SQSTM1 Antikörper (AA 232-356))

Black line: Control Antigen (100 ng), Purple line: Antigen(10 ng), Blue line: Antigen (50 ng), Red line: Antigen (100 ng), (SQSTM1 Antikörper (AA 232-356))

ELISA

Flow cytometric analysis of HEK293 cells using SQSTM1 mouse mAb (green) and negative control (red). (SQSTM1 Antikörper (AA 232-356))

FACS

Western blot analysis using SQSTM1 mAb against human SQSTM1 recombinant protein. (SQSTM1 Antikörper (AA 232-356))

Western blot analysis using SQSTM1 mAb against HEK293 (1) and SQSTM1 (AA: 232-356)-hIgGFc transfected HEK293 (2) cell lysate. (SQSTM1 Antikörper (AA 232-356))

Immunohistochemical analysis of paraffin-embedded cervical cancer tissues using SQSTM1 mouse mAb with DAB staining. (SQSTM1 Antikörper (AA 232-356))

IHC

Immunohistochemical analysis of paraffin-embedded bladder cancer tissues using SQSTM1 mouse mAb with DAB staining. (SQSTM1 Antikörper (AA 232-356))

IHC

7 Abbildungen

(1 reference)

Produktnummer ABIN1724836

Kurzübersicht für SQSTM1 Antikörper (AA 232-356) (ABIN1724836)

Target

Alle SQSTM1 Antikörper anzeigen

SQSTM1 (Sequestosome 1 (SQSTM1))

Reaktivität

Human

Wirt

Maus

Klonalität

Monoklonal

Konjugat

Dieser SQSTM1 Antikörper ist unkonjugiert

Applikation

Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Klon

5H7E2

Discover our top product SQSTM1 Primärantikörper

Bindungsspezifität
17

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11

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9

9

8

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7

6

4

3

2

2

2

2

2

2

2

2

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1

1

1

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1
AA 232-356

Verwendungszweck

SQSTM1 Antibody

Aufreinigung

Purified antibody

Immunogen

Purified recombinant fragment of human SQSTM1 (AA: 232-356) expressed in E. Coli.

Isotyp

IgG1
anti-Sequestosome 1 (SQSTM1) (AA 317-346) antibody
SQSTM1 Reaktivität: Human, Maus WB, IF, IHC (p) Wirt: Kaninchen Polyclonal RB4614 unconjugated

anti-Sequestosome 1 (SQSTM1) antibody
KO Validated SQSTM1 Reaktivität: Human WB, IF, IP, ICC, FACS, IHC (p), PLA Wirt: Kaninchen Polyclonal unconjugated

anti-Sequestosome 1 (SQSTM1) (AA 51-150) antibody
SQSTM1 Reaktivität: Human, Maus, Ratte, Rind (Kuh) WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

anti-Sequestosome 1 (SQSTM1) (AA 1-440) antibody
SQSTM1 Reaktivität: Human WB, IHC, IF, IP Wirt: Kaninchen Polyclonal unconjugated

anti-Sequestosome 1 (SQSTM1) (AA 1-440) antibody
SQSTM1 Reaktivität: Human WB, ELISA, IF Wirt: Maus Monoclonal 2C11 unconjugated

anti-Sequestosome 1 (SQSTM1) (AA 136-400) antibody
SQSTM1 Reaktivität: Human WB, IHC, IP, ICC, FACS Wirt: Kaninchen Polyclonal unconjugated

anti-Sequestosome 1 (SQSTM1) antibody
KO Validated SQSTM1 Reaktivität: Human WB, IHC, IF, IP Wirt: Kaninchen Monoclonal unconjugated

anti-Sequestosome 1 (SQSTM1) (C-Term) antibody
SQSTM1 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Sequestosome 1 (SQSTM1) antibody
SQSTM1 Reaktivität: Human, Affe WB, IHC, IF, FACS, IHC (p) Wirt: Maus Monoclonal 5A2 unconjugated

anti-Sequestosome 1 (SQSTM1) (AA 69-96), (N-Term) antibody
SQSTM1 Reaktivität: Human, Maus, Ratte WB, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

ELISA: 1/10000
FCM: 1/200 - 1/400

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Inoue, Suzuki, Mitsuishi, Miki, Suzuki, Sugawara, Watanabe, Sakurada, Endo, Uruno, Sasano, Nakagawa, Satoh, Tanaka, Kubo, Motohashi, Yamamoto: "Accumulation of p62/SQSTM1 is associated with poor prognosis in patients with lung adenocarcinoma." in: Cancer science, Vol. 103, Issue 4, pp. 760-6, (2012) (PubMed).
Target

SQSTM1 (Sequestosome 1 (SQSTM1))

Andere Bezeichnung

SQSTM1

Hintergrund

This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.

Molekulargewicht

47.7 kDa

Gen-ID

8878

UniProt

Q13501

Pathways

NF-kappaB Signalweg, Neurotrophin Signalübertragung, Autophagie