FGF4 Antikörper (AA 62-123)

Produktnummer ABIN1724833

Dieses Maus Monoklonal-Antikörper erkennt spezifisch FGF4 in ELISA. Er zeigt eine Reaktivität gegenüber Human und wurde in 2+ Publikationen erwähnt.

Kurzübersicht für FGF4 Antikörper (AA 62-123) (ABIN1724833)

Target: FGF4 (Fibroblast Growth Factor 4 (FGF4))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser FGF4 Antikörper ist unkonjugiert

Applikation: ELISA

Klon: 2D7D5

Produktdetails anti-FGF4 Antikörper

Bindungsspezifität: AA 62-123

Verwendungszweck: FGF4 Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human FGF4 (AA: 62-123) expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-FGF4 Antikörper (ABIN1724833)

Johannesson, Ståhlberg, Ameri, Sand, Norrman, Semb: "FGF4 and retinoic acid direct differentiation of hESCs into PDX1-expressing foregut endoderm in a time- and concentration-dependent manner." in: PLoS ONE, Vol. 4, Issue 3, pp. e4794, (2009) (PubMed).

Mayshar, Rom, Chumakov, Kronman, Yayon, Benvenisty: "Fibroblast growth factor 4 and its novel splice isoform have opposing effects on the maintenance of human embryonic stem cell self-renewal." in: Stem cells (Dayton, Ohio), Vol. 26, Issue 3, pp. 767-74, (2008) (PubMed).

Details zu FGF4

Target: FGF4 (Fibroblast Growth Factor 4 (FGF4))

Andere Bezeichnung: FGF4

Hintergrund: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its oncogenic transforming activity. This gene and FGF3, another oncogenic growth factor, are located closely on chromosome 11. Co-amplification of both genes was found in various kinds of human tumors. Studies on the mouse homolog suggested a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway.

Molekulargewicht: 22 kDa

Gen-ID: 2249

UniProt: P08620

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Stem Cell Maintenance