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Integrin Alpha2b Antikörper (AA 45-149)

Name: Integrin Alpha2b Antikörper (AA 45-149)
Brand: antibodies-online
SKU: ABIN1724822
Price: 640.59 EUR
Availability: InStock

Der Maus Monoklonal Anti-Integrin Alpha2b-Antikörper wurde für FACS, IHC und ELISA validiert. Er ist geeignet, Integrin Alpha2b in Proben von Human zu detektieren. Es sind 2+ Publikationen verfügbar.

Flow cytometric analysis of HL60 cells using ITGA2B mouse mAb (green) and negative control (purple). (Integrin Alpha2b Antikörper (AA 45-149))

FACS

Immunohistochemical analysis of paraffin-embedded rectum cancer tissues using ITGA2B mouse mAb with DAB staining. (Integrin Alpha2b Antikörper (AA 45-149))

IHC

Western blot analysis using ITGA2B mAb against human ITGA2B recombinant protein. (Integrin Alpha2b Antikörper (AA 45-149))

Black line: Control Antigen (100 ng), Purple line: Antigen(10 ng), Blue line: Antigen (50 ng), Red line: Antigen (100 ng), (Integrin Alpha2b Antikörper (AA 45-149))

ELISA

Western blot analysis using ITGA2B mAb against HEK293 (1) and ITGA2B (AA: 45-149)-hIgGFc transfected HEK293 (2) cell lysate. (Integrin Alpha2b Antikörper (AA 45-149))

Immunohistochemical analysis of paraffin-embedded cervical cancer tissues using ITGA2B mouse mAb with DAB staining. (Integrin Alpha2b Antikörper (AA 45-149))

IHC

6 Abbildungen

(2 Referenzen)

Produktnummer ABIN1724822

Datenblatt (PDF)

Kurzübersicht für Integrin Alpha2b Antikörper (AA 45-149) (ABIN1724822)

Target

Alle Integrin Alpha2b (CD41) Antikörper anzeigen

Integrin Alpha2b (CD41)

Reaktivität

Human

Wirt

Maus

Klonalität

Monoklonal

Konjugat

Dieser Integrin Alpha2b Antikörper ist unkonjugiert

Applikation

Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA

Klon

2E10C9

Bindungsspezifität
16

8

5

4

3

3

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 45-149

Verwendungszweck

ITGA2B Antibody

Aufreinigung

Ascitic fluid

Immunogen

Purified recombinant fragment of human ITGA2B (AA: 45-149) expressed in E. Coli.

Isotyp

IgG1
anti-Integrin Alpha2b (CD41) (AA 45-149) antibody
CD41 Reaktivität: Human FACS, WB, IHC, ELISA Wirt: Maus Monoclonal unconjugated

anti-Integrin Alpha2b (CD41) (AA 351-450) antibody
CD41 Reaktivität: Human, Ratte FACS, WB, ELISA, IHC (fro), IHC (p), IF (p), IF (cc) Wirt: Kaninchen Polyclonal unconjugated

anti-Integrin Alpha2b (CD41) antibody
CD41 Reaktivität: Maus FACS, ELISA, IP, IHC (fro), IHC (p), Func Wirt: Ratte Monoclonal MWReg30 unconjugated

anti-Integrin Alpha2b (CD41) antibody
CD41 Reaktivität: Maus FACS, ELISA, IP, IHC (fro), IHC (p) Wirt: Ratte Monoclonal MWReg30 unconjugated

anti-Integrin Alpha2b (CD41) antibody
CD41 Reaktivität: Human, Non-Human Primate FACS, IHC (fro) Wirt: Maus Monoclonal HIP2 unconjugated

anti-Integrin Alpha2b (CD41) antibody (Biotin)
CD41 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-06 Biotin

anti-Integrin Alpha2b (CD41) antibody (FITC)
CD41 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-06 FITC

anti-Integrin Alpha2b (CD41) (AA 677-711), (C-Term) antibody
CD41 Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated

anti-Integrin Alpha2b (CD41) antibody
CD41 Reaktivität: Human, Non-Human Primate FACS, IHC (fro) Wirt: Maus Monoclonal HIP8 unconjugated

anti-Integrin Alpha2b (CD41) antibody (PE)
CD41 Reaktivität: Maus FACS Wirt: Ratte Monoclonal MWReg30 PE

Applikationshinweise

ELISA: 1/10000
FCM: 1/200 - 1/400

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Park, Chung, Lee, Park, Kim, Kim: "Novel and recurrent mutations of ITGA2B and ITGB3 genes in Korean patients with Glanzmann thrombasthenia." in: Pediatric blood & cancer, Vol. 59, Issue 2, pp. 335-8, (2012) (PubMed).

Nurden, Fiore, Nurden, Pillois: "Glanzmann thrombasthenia: a review of ITGA2B and ITGB3 defects with emphasis on variants, phenotypic variability, and mouse models." in: Blood, Vol. 118, Issue 23, pp. 5996-6005, (2011) (PubMed).
Target

Integrin Alpha2b (CD41)

Andere Bezeichnung

ITGA2B

Hintergrund

ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.

Molekulargewicht

113.4 kDa

Gen-ID

3674

UniProt

P08514

Pathways

Integrin Complex