PDE1B Antikörper (AA 370-536)
Kurzübersicht für PDE1B Antikörper (AA 370-536) (ABIN1724781)
Target
Alle PDE1B Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 370-536
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Verwendungszweck
- PDE1B Antibody
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Aufreinigung
- Ascitic fluid
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Immunogen
- Purified recombinant fragment of human PDE1B (AA: 370-536 ) expressed in E. Coli.
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Isotyp
- IgG1
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Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Ascitic fluid containing 0.03 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Cyclic nucleotide phosphodiesterase PDE1C1 in human cardiac myocytes." in: The Journal of biological chemistry, Vol. 282, Issue 45, pp. 32749-57, (2007) (PubMed).
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: "Cyclic nucleotide phosphodiesterase PDE1C1 in human cardiac myocytes." in: The Journal of biological chemistry, Vol. 282, Issue 45, pp. 32749-57, (2007) (PubMed).
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- PDE1B (phosphodiesterase 1B, Calmodulin-Dependent (PDE1B))
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Andere Bezeichnung
- PDE1B
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Hintergrund
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The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
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Molekulargewicht
- 61.4 kDa
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Gen-ID
- 5153
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UniProt
- Q01064
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Pathways
- Neurotrophin Signalübertragung, cAMP Metabolic Process, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma
Target
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