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PDE1B Antikörper (AA 370-536)

PDE1B Reaktivität: Human ELISA, IHC, FACS Wirt: Maus Monoclonal 5C4A3 unconjugated
Produktnummer ABIN1724781
  • Target Alle PDE1B Antikörper anzeigen
    PDE1B (phosphodiesterase 1B, Calmodulin-Dependent (PDE1B))
    Bindungsspezifität
    • 8
    • 7
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 370-536
    Reaktivität
    • 41
    • 24
    • 16
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 38
    • 8
    Maus
    Klonalität
    • 37
    • 9
    Monoklonal
    Konjugat
    • 25
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PDE1B Antikörper ist unkonjugiert
    Applikation
    • 36
    • 24
    • 15
    • 11
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
    Verwendungszweck
    PDE1B Antibody
    Aufreinigung
    Ascitic fluid
    Immunogen
    Purified recombinant fragment of human PDE1B (AA: 370-536 ) expressed in E. Coli.
    Klon
    5C4A3
    Isotyp
    IgG1
  • Applikationshinweise

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Vandeput, Wolda, Krall, Hambleton, Uher, McCaw, Radwanski, Florio, Movsesian: "Cyclic nucleotide phosphodiesterase PDE1C1 in human cardiac myocytes." in: The Journal of biological chemistry, Vol. 282, Issue 45, pp. 32749-57, (2007) (PubMed).

  • Target
    PDE1B (phosphodiesterase 1B, Calmodulin-Dependent (PDE1B))
    Andere Bezeichnung
    PDE1B (PDE1B Produkte)
    Hintergrund
    The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

    Molekulargewicht
    61.4 kDa
    Gen-ID
    5153
    UniProt
    Q01064
    Pathways
    Neurotrophin Signalübertragung, cAMP Metabolic Process, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma
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