MAP1LC3A Antikörper (AA 1-121)

Produktnummer ABIN1724767

Dieses Maus Monoklonal-Antikörper erkennt spezifisch MAP1LC3A in IHC, ELISA und FACS. Er zeigt eine Reaktivität gegenüber Human und wurde in 2+ Publikationen erwähnt.

Kurzübersicht für MAP1LC3A Antikörper (AA 1-121) (ABIN1724767)

Target: MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MAP1LC3A Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Klon: 5B10D8

Produktdetails anti-MAP1LC3A Antikörper

Bindungsspezifität: AA 1-121

Verwendungszweck: MAP1LC3A Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human MAP1LC3A (AA: 1-121) expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-MAP1LC3A Antikörper (ABIN1724767)

Jiang, Shao, Wang, Yan, Liu: "Decreased expression of Beclin-1 and LC3 in human lung cancer." in: Molecular biology reports, Vol. 39, Issue 1, pp. 259-67, (2011) (PubMed).

Han, Sun, Wang, Cai, Lou, Sun, Zhao: "Overexpression of microtubule-associated protein-1 light chain 3 is associated with melanoma metastasis and vasculogenic mimicry." in: The Tohoku journal of experimental medicine, Vol. 223, Issue 4, pp. 243-51, (2011) (PubMed).

Details zu MAP1LC3A

Target: MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))

Andere Bezeichnung: MAP1LC3A

Hintergrund: MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. The protein encoded by this gene is one of the light chain subunits and can associate with either MAP1A or MAP1B. Two transcript variants encoding different isoforms have been found for this gene. The expression of variant 1 is suppressed in many tumor cell lines, suggesting that may be involved in carcinogenesis.

Molekulargewicht: 14.3 kDa

Gen-ID: 84557

UniProt: Q9H492

Pathways: Autophagie