DKK3 Antikörper

Produktnummer ABIN1724727

Dieses Anti-DKK3-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von DKK3 in WB, ELISA und FACS. Geeignet für Human und Affe. Dieses Primary Antibody wurde in 3+ Publikationen zitiert.

Kurzübersicht für DKK3 Antikörper (ABIN1724727)

Target: DKK3

Reaktivität: Human, Affe

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser DKK3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Klon: 4G7

Produktdetails anti-DKK3 Antikörper

Verwendungszweck: DKK3 Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human DKK3 expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-DKK3 Antikörper (ABIN1724727)

Pei, Kano, Iijima, Morishita, Inadome, Noguchi: "Overexpression of Dickkopf 3 in hepatoblastomas and hepatocellular carcinomas." in: Virchows Archiv : an international journal of pathology, Vol. 454, Issue 6, pp. 639-46, (2009) (PubMed).

Kurose, Sakaguchi, Nasu, Ebara, Kaku, Kariyama, Arao, Miyazaki, Tsushima, Namba, Kumon, Huh: "Decreased expression of REIC/Dkk-3 in human renal clear cell carcinoma." in: The Journal of urology, Vol. 171, Issue 3, pp. 1314-8, (2004) (PubMed).

Persson, Rosenquist, Sommarin: "Identification of a novel calreticulin isoform (Crt2) in human and mouse." in: Gene, Vol. 297, Issue 1-2, pp. 151-8, (2002) (PubMed).

Details zu DKK3

Target: DKK3

Hintergrund: Dkk-3 (Dickkopf-3) is a member of the dickkopf family. It is a 350 amino acid secreted glycoprotein that is composed of an N-terminal signal peptide and two conserved cysteine-rich domains, which are separated by a 12 amino acid linker region. This secreted protein is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene.

Molekulargewicht: 38 kDa

Gen-ID: 27122

UniProt: Q9UBP4