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DKK3 Antikörper (AA 31-130)

Name: DKK3 Antikörper (AA 31-130)
SKU: ABIN749123
Price: 384.62 EUR
Availability: InStock

Reaktivität: Maus, Kaninchen WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-DKK3 Polyclonal Antibody, Unconjugated (ABIN749123) followed by conjugation to the secondary antibody and DAB staining (DKK3 Antikörper (AA 31-130))

IHC

Formalin-fixed and paraffin embedded rat buccal mucosa cancer labeled with Anti-DKK3 Polyclonal Antibody, Unconjugated (ABIN749123) at 1:200 followed by conjugation to the secondary antibody and DAB staining (DKK3 Antikörper (AA 31-130))

IHC

Paraformaldehyde-fixed, paraffin embedded mouse brain, Antigen retrieval by boiling in sodium citrate buffer (pH6) for 15min, Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes, Blocking buffer (normal goat serum) at 37°C for 20min, Antibody incubation with DKK3 Polyclonal Antibody (bs-2688R) at 1:400 overnight at 4°C, followed by a conjugated secondary and DAB staining. (DKK3 Antikörper (AA 31-130))

IHC (p)

3 Abbildungen

Produktnummer ABIN749123

Datenblatt (PDF)

Target Alle DKK3 Antikörper anzeigen

DKK3
Bindungsspezifität
14

11

9

8

8

1

1

1

1

1

1

1

1

1

1

1

1
AA 31-130
Reaktivität
56

34

16

14

2

2

2

1

1

1

1
Maus, Kaninchen
Wirt
67

5

2

1
Kaninchen
Passende Sekundärantikörper
Klonalität
68

7
Polyklonal
Konjugat
34

6

6

5

4

3

2

2

2

2

2

2

1

1

1

1

1
Dieser DKK3 Antikörper ist unkonjugiert
Applikation
56

37

29

12

12

7

6

5

4

3

3

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität

Maus, Kaninchen

Homologie

Human,Rat,Cow,Pig,Horse

Aufreinigung

Purified by Protein A.

Immunogen

KLH conjugated synthetic peptide derived from human DKK3

Isotyp

IgG

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Reaktivität: Human WB, IF Wirt: Kaninchen Monoclonal unconjugated

Applikationshinweise

WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 μg/μL

Buffer

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel

ProClin

Vorsichtsmaßnahmen

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit

12 months
Target

DKK3

Abstract

DKK3 Produkte

Synonyme

REIC antikoerper, RIG antikoerper, reic antikoerper, dkk-3 antikoerper, AW061014 antikoerper, C87148 antikoerper, Reic antikoerper, p29 antikoerper, dickkopf WNT signaling pathway inhibitor 3 antikoerper, dickkopf WNT signaling pathway inhibitor 3 S homeolog antikoerper, DKK3 antikoerper, dkk3 antikoerper, dkk3.S antikoerper, Dkk3 antikoerper

Hintergrund

Synonyms: RIG, REIC, Dickkopf-related protein 3, Dickkopf-3, Dkk-3, hDkk-3, DKK3, UNQ258/PRO295
Background: Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity).

Gen-ID

27122

UniProt

Q9UBP4