DKK3 Antikörper
-
- Target Alle DKK3 Antikörper anzeigen
- DKK3
-
Reaktivität
- Human, Maus, Ratte
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser DKK3 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
- Spezifität
- DKK3 Antibody detects endogenous levels of total DKK3
- Kreuzreaktivität
- Human, Maus, Ratte (Rattus)
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human DKK3
- Isotyp
- IgG
- Top Product
- Discover our top product DKK3 Primärantikörper
-
-
- Applikationshinweise
- WB 1:500-1:2000 IHC 1:50-1:200, IF/ICC 1:100-1:500
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C.Stable for 12 months from date of receipt
- Haltbarkeit
- 12 months
-
- Target
- DKK3
- Abstract
- DKK3 Produkte
- Synonyme
- REIC antikoerper, RIG antikoerper, reic antikoerper, dkk-3 antikoerper, AW061014 antikoerper, C87148 antikoerper, Reic antikoerper, p29 antikoerper, dickkopf WNT signaling pathway inhibitor 3 antikoerper, dickkopf WNT signaling pathway inhibitor 3 S homeolog antikoerper, DKK3 antikoerper, dkk3 antikoerper, dkk3.S antikoerper, Dkk3 antikoerper
- Hintergrund
-
Description: Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity).
Gene: DKK3
- Molekulargewicht
- 38kDa
- Gen-ID
- 27122
- UniProt
- Q9UBP4
-