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MSH6 Antikörper

MSH6 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 3A10H7 unconjugated
Produktnummer ABIN1724694
  • Target Alle MSH6 Antikörper anzeigen
    MSH6 (MutS Homolog 6 (E. Coli) (MSH6))
    Reaktivität
    • 79
    • 37
    • 31
    • 9
    • 5
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 58
    • 18
    • 3
    Maus
    Klonalität
    • 46
    • 33
    Monoklonal
    Konjugat
    • 47
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MSH6 Antikörper ist unkonjugiert
    Applikation
    • 54
    • 27
    • 24
    • 22
    • 14
    • 13
    • 12
    • 8
    • 8
    • 7
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    Aufreinigung
    purified
    Immunogen
    Purified recombinant fragment of MSH6 expressed in E. coli.
    Klon
    3A10H7
    Isotyp
    IgG1
    Top Product
    Discover our top product MSH6 Primärantikörper
  • Applikationshinweise
    ELISA: 1:10000, WB: 1:500 - 1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    4°C, -20°C for long term storage
  • Hess, Mendillo, Mazur, Kolodner: "Biochemical basis for dominant mutations in the Saccharomyces cerevisiae MSH6 gene." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 3, pp. 558-63, (2006) (PubMed).

    Lynch, Lynch: "What the physician needs to know about Lynch syndrome: an update." in: Oncology (Williston Park, N.Y.), Vol. 19, Issue 4, pp. 455-63; discussion 463-4, 466, 469, (2005) (PubMed).

  • Target
    MSH6 (MutS Homolog 6 (E. Coli) (MSH6))
    Andere Bezeichnung
    MSH6 (MSH6 Produkte)
    Synonyme
    GTBP antikoerper, GTMBP antikoerper, HNPCC5 antikoerper, HSAP antikoerper, p160 antikoerper, cb326 antikoerper, wu:fb36c12 antikoerper, LOC100227810 antikoerper, AU044881 antikoerper, AW550279 antikoerper, Gtmbp antikoerper, mutS homolog 6 antikoerper, mutS homolog 6 (E. coli) antikoerper, DNA mismatch repair protein antikoerper, MSH6 antikoerper, msh6 antikoerper, Msh6 antikoerper
    Hintergrund

    Description: Defects in MSH6 are a cause of hereditary non-polyposis colorectal cancer (HNPCC) (Lynch syndrome). HNPCC is an autosomal, dominantly inherited disease associated with marked increase in cancer susceptibility. It is characterized by a familial predisposition to early onset colorectal carcinoma (crc) and extra-colonic cancers of the gastrointestinal, urological and female reproductive tracts. HNPCC is reported to be the most common form of inherited colorectal cancer in the western world. MSH6 is central to mismatch DNA repair.

    Aliases: GTBP, HSAP, HNPCC5

    Gen-ID
    2956
    HGNC
    2956
    Pathways
    DNA Reparatur, Chromatin Binding, Production of Molecular Mediator of Immune Response
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