Retinoblastoma 1 Antikörper
(1 reference)Kurzübersicht für Retinoblastoma 1 Antikörper (ABIN1724645)
Target
Alle Retinoblastoma 1 (RB1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Immunogen
- Purified recombinant fragment of human RB expressed in E. Coli.
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Isotyp
- IgG1
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anti-Retinoblastoma 1 (RB1) (pSer780) antibody
RB1 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Retinoblastoma 1 (RB1) (AA 586-615) antibodyRB1 Reaktivität: Human WB, IF, IHC (p) Wirt: Kaninchen Polyclonal RB7977 unconjugated
anti-Retinoblastoma 1 (RB1) (AA 858-886), (C-Term) antibodyRB1 Reaktivität: Human WB, IHC (p), FACS Wirt: Kaninchen Polyclonal RB20715 unconjugated
anti-Retinoblastoma 1 (RB1) (pSer612) antibodyRB1 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB7659 unconjugated
anti-Retinoblastoma 1 (RB1) (pSer780) antibodyRB1 Reaktivität: Human WB, IHC Wirt: Kaninchen Monoclonal unconjugated
anti-Retinoblastoma 1 (RB1) (C-Term) antibodyRB1 Reaktivität: Human WB, IF, IP, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Retinoblastoma 1 (RB1) (C-Term) antibodyRB1 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Retinoblastoma 1 (RB1) (pSer807) antibodyRB1 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Ascitic fluid containing 0.03 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Glutamic acid mutagenesis of retinoblastoma protein phosphorylation sites has diverse effects on function." in: Oncogene, Vol. 19, Issue 4, pp. 562-70, (2000) (PubMed).
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: "Glutamic acid mutagenesis of retinoblastoma protein phosphorylation sites has diverse effects on function." in: Oncogene, Vol. 19, Issue 4, pp. 562-70, (2000) (PubMed).
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- Retinoblastoma 1 (RB1)
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Andere Bezeichnung
- RB
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Hintergrund
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The Rb protein regulates differentiation, apoptosis, and cell cycle control by coordinating the cell cycle at G1-S with transcriptional machinery. During G1, cyclin D-dependent kinase-mediated phosphorylation of Rb at Ser-795 marks the conversion of Rb from a transcriptionally repressive, hypophosphorylated state to an inactive, phosphorylated state, which may be sustained through mitosis by differential phosphorylation of up to 16 putative serine or threonine residues. Pediatric cancer retinoblastoma and the formation of other human tumors can be attributed to mutations in the retinoblastoma tumor suppressor gene(Rb).
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Gen-ID
- 5925
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HGNC
- 5925
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UniProt
- P06400
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Pathways
- Zellzyklus, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, DNA Replication, Maintenance of Protein Location, Synthesis of DNA, Autophagie
Target
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