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FANCD2 Antikörper (pSer1404)

Der Kaninchen Polyklonal Anti-FANCD2-Antikörper wurde für ELISA, IHC (p), IF (cc), IF (p), FACS, ICC und IHC (fro) validiert. Er ist geeignet, FANCD2 in Proben von Human zu detektieren.
Produktnummer ABIN1715081

Kurzübersicht für FANCD2 Antikörper (pSer1404) (ABIN1715081)

Target

Alle FANCD2 Antikörper anzeigen
FANCD2 (Fanconi Anemia, Complementation Group D2 (FANCD2))

Reaktivität

  • 70
  • 27
  • 24
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 70
  • 1
Kaninchen

Klonalität

  • 60
  • 11
Polyklonal

Konjugat

  • 31
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser FANCD2 Antikörper ist unkonjugiert

Applikation

  • 28
  • 21
  • 19
  • 13
  • 13
  • 13
  • 8
  • 7
  • 7
  • 7
  • 3
  • 1
  • 1
ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Bindungsspezifität

    • 15
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer1404

    Kreuzreaktivität

    Human

    Homologie

    Cow,Sheep,Pig,Horse,Rabbit

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic phosphopeptide derived from human FANCD2 around the phosphorylation site of Ser1404

    Isotyp

    IgG
  • Applikationshinweise

    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    Haltbarkeit

    12 months
  • Target

    FANCD2 (Fanconi Anemia, Complementation Group D2 (FANCD2))

    Andere Bezeichnung

    FANCD2

    Hintergrund

    Synonyms: FANCD2 phospho S1404, FANCD2 phospho Ser1404, p-FANCD2 phospho S1404, FA 4, FA D2, FA4, FAC D2, FACD 2, FACD, FACD2, FAD, FAD2, FANC D2, FANCD 2, FANCD, Protein FACD2, Type 4 Fanconi pancytopenia, FACD2_HUMAN, Fanconi anemia group D2 protein, Protein FACD2.

    Background: Fanconi Anemia (FANC) is a human autosomal-recessive cancer susceptibility disorder characterized by congenital defects, progressive bone marrow failure, and cellular hypersensitivity to mitomycin C (MMC). The FANC subunit D2 protein is vital for cellular resistance to DNA cross-linking and the arrest of DNA synthesis after ionizing radiation. DNA damage activates the monoubiquitination of FANC D2, targeting nuclear foci containing the BRCA 1 protein.

    Gen-ID

    2177

    Pathways

    DNA Reparatur
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