SPTA1 Antikörper (AA 2151-2350)

Produktnummer ABIN1714958

Der Kaninchen Polyklonal Anti-SPTA1-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, SPTA1 in Proben von Maus und Ratte zu detektieren.

Kurzübersicht für SPTA1 Antikörper (AA 2151-2350) (ABIN1714958)

Target: SPTA1 (Spectrin alpha 1, Erythrocytic (SPTA1))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPTA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-SPTA1 Antikörper

Bindungsspezifität: AA 2151-2350

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Spectrin alpha chain, erythrocytic 1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu SPTA1

Target: SPTA1 (Spectrin alpha 1, Erythrocytic (SPTA1))

Andere Bezeichnung: Spectrin alpha chain, erythrocytic 1

Hintergrund:

Synonyms: Alpha I spectrin, EL 2, EL2, Elliptocytosis 2, Elliptocytosis2, Erythrocyte alpha spectrin, erythrocyte, Erythroid alpha spectrin, Erythroid alpha-spectrin, Erythroid spectrin alpha, HPP, HS3, Spectrin alpha chain, Spectrin alpha chain erythrocyte, Spectrin alpha erythrocytic 1, SPH3, SPTA 1, SPTA, SPTA1, SPTA1_HUMAN, Spectrin alpha chain, erythrocytic 1.

Background: Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is a tetramer made up of alpha-beta dimers linked in a head-to-head arrangement. This gene is one member of a family of alpha-spectrin genes. The encoded protein is primarily composed of 22 spectrin repeats which are involved in dimer formation. It forms weaker tetramer interactions than non-erythrocytic alpha spectrin, which may increase the plasma membrane elasticity and deformability of red blood cells. Mutations in this gene result in a variety of hereditary red blood cell disorders, including elliptocytosis type 2, pyropoikilocytosis, and spherocytic hemolytic anemia. [provided by RefSeq, Jul 2008].

Gen-ID: 6708

Pathways: Regulation of Actin Filament Polymerization