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SPTA1 Antikörper (AA 356-475)

SPTA1 Reaktivität: Human ELISA, Coat, IHC (f) Wirt: Maus Monoclonal SPTA1-1810 unconjugated
Produktnummer ABIN6938436
  • Target Alle SPTA1 Antikörper anzeigen
    SPTA1 (Spectrin alpha 1, Erythrocytic (SPTA1))
    Bindungsspezifität
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 356-475
    Reaktivität
    • 24
    • 12
    • 4
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 18
    • 7
    Maus
    Klonalität
    • 14
    • 11
    Monoklonal
    Konjugat
    • 18
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SPTA1 Antikörper ist unkonjugiert
    Applikation
    • 16
    • 9
    • 8
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    ELISA, Coating (Coat), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    Spezifität
    Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. Spectrins function as membrane organizers and stabilizers, composed of non-homologous ) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function.
    Kreuzreaktivität (Details)
    Human.
    Aufreinigung
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    Immunogen
    Recombinant human SPTA fragment (around aa356-475) (exact sequence is proprietary)
    Klon
    SPTA1-1810
    Isotyp
    IgG2c kappa
    Top Product
    Discover our top product SPTA1 Primärantikörper
  • Applikationshinweise

    Known_Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT) (Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: Jurkat cells. Placenta or Tonsil.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    Konservierungsmittel
    Azide free
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    Haltbarkeit
    24 months
  • Target
    SPTA1 (Spectrin alpha 1, Erythrocytic (SPTA1))
    Andere Bezeichnung
    SPTA1 (SPTA1 Produkte)
    Synonyme
    Spna1 antikoerper, AF093576 antikoerper, AI451697 antikoerper, Spna-1 antikoerper, ha antikoerper, ihj antikoerper, nmf4 antikoerper, sph antikoerper, EL2 antikoerper, HPP antikoerper, HS3 antikoerper, SPH3 antikoerper, SPTA antikoerper, spectrin, alpha, erythrocytic 1 antikoerper, spectrin alpha, erythrocytic 1 antikoerper, Spta1 antikoerper, SPTA1 antikoerper
    Hintergrund
    Alpha I spectrin, Elliptocytosis 2 (EL2), Erythrocyte alpha spectrin, Erythroid alpha-spectrin, HPP, HS3, Spectrin alpha erythrocytic 1, SPH3, SPTA1,Spectrin Alpha 1 (Erythrocyte Marker)
    Cellular localisation: Cytoplasmic and Cell Surface
    Molekulargewicht
    240kDa
    Gen-ID
    6708, 119825
    UniProt
    P02549
    Pathways
    Regulation of Actin Filament Polymerization
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