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Leupaxin (LPXN) Antikörper Primary Antibody

LPXN Reaktivität: Human, Maus, Ratte IF (p), IHC (p), WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1713856
$339.90
Zzgl. Versandkosten $45.00
100 μL
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 4 bis 6 Werktagen
  • Target
    Leupaxin (LPXN)
    Reaktivität
    Human, Maus, Ratte
    • 43
    • 28
    • 19
    • 1
    Wirt
    Kaninchen
    • 42
    • 2
    Klonalität
    Polyklonal
    • 44
    Konjugat
    Unkonjugiert
    • 13
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Applikation
    Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
    • 28
    • 21
    • 12
    • 6
    • 4
    • 1
    • 1
    • 1
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Leupaxin
    Isotyp
    IgG
  • Applikationshinweise
    WB 1:100-1000
    IHC-P 1:100-500
    IF(IHC-P) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C
    Haltbarkeit
    12 months
  • Target
    Leupaxin (LPXN)
    Andere Bezeichnung
    Leupaxin (LPXN Antibody Abstract)
    Synonyme
    LDPL, 4933402K05Rik, A530083L21Rik, AV278559, MGC140379, leupaxin, hypothetical protein, Leupaxin, LPXN, Lpxn, lpxn, PAAG_03110, PGTG_11441
    Hintergrund

    Leupaxin is a 386 amino acid cytoplasmic protein and member of the paxillin family. Leupaxin is highly expressed in lymphoid tissues such as spleen, lymph node, thymus and appendix, with low expression in bone marrow and fetal liver. Consisting of four leucine-rich LD-motifs at the N-terminus and four LIM domains at the C-terminus, leupaxin associates with a member of the focal adhesion kinase family, PYK2, in lymphoid cells. The leupaxin and PYK2 complex is involved in cell type-specific signaling in which it regulates signaling at sites of adhesion. Leupaxin is a substrate for tyrosine kinase in lymphoid cells and is suggested to participate in and be regulated by tyrosine kinase activity. Leupaxin may be a potential progression marker for a subset of prostate cancer and may act as a novel coactivator of the androgen receptor.

    Synonyms: LDLP, LDPL, LPXN, LPXN_HUMAN.

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