AGPS Antikörper (AA 31-130) (HRP)

Produktnummer ABIN1712481

Dieses Anti-AGPS-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von AGPS in ELISA, IHC (p) und IHC (fro). Geeignet für Ratte.

Kurzübersicht für AGPS Antikörper (AA 31-130) (HRP) (ABIN1712481)

Target: AGPS (Alkylglycerone Phosphate Synthase (AGPS))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AGPS Antikörper ist konjugiert mit HRP

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-AGPS Antikörper (HRP)

Bindungsspezifität: AA 31-130

Kreuzreaktivität: Ratte

Homologie: Human,Mouse,Cow,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human AGPS/Alkyl-DHAP synthase

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu AGPS

Target: AGPS (Alkylglycerone Phosphate Synthase (AGPS))

Andere Bezeichnung: AGPS/Alkyl-DHAP synthase

Hintergrund:

Synonyms: AAG5, ADAP-S, ADAS, ADAS_HUMAN, ADHAPS, ADPS, Aging associated gene 5 protein, Aging-associated gene 5 protein, AGPS, ALDHPSY, Alkyl-DHAP synthase, Alkyldihydroxyacetonephosphate synthase, Alkyldihydroxyacetonephosphate synthase, peroxisomal, Alkylglycerone phosphate synthase, Alkylglycerone-phosphate synthase, peroxisomal.

Background: AGPS is a 658 amino acid enzyme that is required for glycerolipid metabolism and ether lipid biosynthesis. Localized to the inner aspect of the peroxisomal membrane, AGPS is likely part of a heterotrimeric complex that is also composed of GNPAT and a modified form of GNPAT. Containing one FAD-binding PCMH-type domain, AGPS utilizes FAD as a cofactor in the synthesis of alkyl-glycerone 3-phophate and a long-chain acid anion from 1-acteyl-glyerone 3-phosphate and a long-chain alcohol. Defects in the gene encoding AGPS results in rhizomelic chondrodysplasia punctata type 3, a disease characterized by vertebral disorders, severe mental retardation, cutaneous lesions, cataracts and rhizomelic shortening of the humerus and femur.

Gen-ID: 8540

Pathways: SARS-CoV-2 Protein Interaktom