RGS14 Antikörper (AA 151-250) (HRP)

Produktnummer ABIN1711085

Der Kaninchen Polyklonal Anti-RGS14-Antikörper wurde für WB, ELISA, IHC (p) und IHC (fro) validiert. Er ist geeignet, RGS14 in Proben von Maus und Ratte zu detektieren.

Kurzübersicht für RGS14 Antikörper (AA 151-250) (HRP) (ABIN1711085)

Target: RGS14 (Regulator of G-Protein Signaling 14 (RGS14))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RGS14 Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-RGS14 Antikörper (HRP)

Bindungsspezifität: AA 151-250

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Cow

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RGS14

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu RGS14

Target: RGS14 (Regulator of G-Protein Signaling 14 (RGS14))

Andere Bezeichnung: RGS14

Hintergrund:

Synonyms: Highly similar to rap1/rap2 interacting protein, OTTHUMP00000223586, OTTHUMP00000223587, Regulation of G protein signaling 14, Regulator of G protein signaling 14, Regulator of G protein signalling 14, Regulator of G-protein signaling 14, RGS 14, RGS14, RGS14_HUMAN.

Background: RGS14 is a member of the regulator of G-protein signaling family. This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco domain. The protein attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of activated, GTP-bound G alpha subunits. Acting as a GTPase activating protein (GAP), the protein increases the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

Gen-ID: 10636

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Platelet-derived growth Factor Receptor Signaling