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FAK Antikörper (pSer910) (FITC)

PTK2 Reaktivität: Maus, Ratte, Xenopus laevis WB, IF (p), IF (cc) Wirt: Kaninchen Polyclonal FITC

Produktnummer ABIN1709684

Datenblatt (PDF)

Target Alle FAK (PTK2) Antikörper anzeigen

FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))
Bindungsspezifität
43

34

30

28

23

22

22

20

16

16

13

11

7

5

5

4

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1
pSer910
Reaktivität
332

277

208

22

20

17

16

12

8

6

6

4

3

3

2

1

1

1

1

1
Maus, Ratte, Xenopus laevis
Wirt
335

20

3

2

1

1
Kaninchen
Passende Sekundärantikörper
Klonalität
329

33
Polyklonal
Konjugat
158

17

15

12

10

10

10

10

10

10

10

10

10

10

10

10

7

7

6

6

6

6

1

1
Dieser FAK Antikörper ist konjugiert mit FITC
Applikation
291

132

132

120

106

68

61

42

31

29

23

5

3

2

2

2
Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Kreuzreaktivität

Maus, Ratte, Xenopus laevis

Homologie

Human,Chicken

Aufreinigung

Purified by Protein A.

Immunogen

KLH conjugated synthetic phosphopeptide derived from human PTK2 around the phosphorylation site of Tyr910

Isotyp

IgG

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anti-PTK2 Protein tyrosine Kinase 2 (PTK2) (AA 700-800) antibody
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anti-PTK2 Protein tyrosine Kinase 2 (PTK2) (AA 798-1041) antibody
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anti-PTK2 Protein tyrosine Kinase 2 (PTK2) (AA 396-423) antibody
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anti-PTK2 Protein tyrosine Kinase 2 (PTK2) (AA 355-490) antibody
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anti-PTK2 Protein tyrosine Kinase 2 (PTK2) (pTyr576) antibody
PTK2 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-PTK2 Protein tyrosine Kinase 2 (PTK2) (AA 821-848), (C-Term) antibody
PTK2 Reaktivität: Human WB, IF, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB20776 unconjugated

anti-PTK2 Protein tyrosine Kinase 2 (PTK2) antibody
PTK2 Reaktivität: Human WB, ELISA, IHC, ICC Wirt: Maus Monoclonal 10H7 unconjugated

anti-PTK2 Protein tyrosine Kinase 2 (PTK2) antibody
PTK2 Reaktivität: Human ELISA, FACS, ICC Wirt: Maus Monoclonal 10H7E9 unconjugated

anti-PTK2 Protein tyrosine Kinase 2 (PTK2) (AA 1-680) antibody
PTK2 Reaktivität: Human WB, PLA Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 μg/μL

Buffer

Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel

ProClin

Vorsichtsmaßnahmen

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung

-20 °C

Informationen zur Lagerung

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit

12 months
Target

FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))

Andere Bezeichnung

FAK (PTK2 Produkte)

Hintergrund

Synonyms: FAK phospho S910, p-FAK phospho S910, FADK 1, FADK, FAK 1, FAK related non kinase polypeptide, FAK1, Focal adhesion kinase 1, FRNK, pp125FAK, Protein tyrosine kinase 2, Protein Tyrosine Kinase Cytoplasmic, PTK 2, FAK1_HUMAN, Focal adhesion kinase-related nonkinase, Protein phosphatase 1 regulatory subunit 71, PPP1R71, Protein-tyrosine kinase 2, p125FAK.
Background: Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Microtubule-induced dephosphorylation at Tyr-397 is crucial for the induction of focal adhesion disassembly. Plays a potential role in oncogenic transformations resulting in increased kinase activity.

Gen-ID

5747

Pathways

Response to Growth Hormone Stimulus, CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling