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OAS3 Antikörper (AA 901-1000) (Cy7)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch OAS3 in WB, IF (cc) und IF (p). Er zeigt eine Reaktivität gegenüber Human und Maus.
Produktnummer ABIN1707766

Kurzübersicht für OAS3 Antikörper (AA 901-1000) (Cy7) (ABIN1707766)

Target

Alle OAS3 Antikörper anzeigen
OAS3 (2'-5' Oligoadenylate Synthetase 3 (OAS3))

Reaktivität

  • 42
  • 15
  • 2
Human, Maus

Wirt

  • 40
  • 1
  • 1
Kaninchen

Klonalität

  • 41
  • 1
Polyklonal

Konjugat

  • 14
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser OAS3 Antikörper ist konjugiert mit Cy7

Applikation

  • 31
  • 16
  • 12
  • 12
  • 5
  • 5
  • 4
  • 4
  • 3
  • 2
  • 1
Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • Bindungsspezifität

    • 14
    • 8
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 901-1000

    Kreuzreaktivität

    Human, Maus

    Homologie

    Rat

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human OAS3

    Isotyp

    IgG
  • Applikationshinweise

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    Haltbarkeit

    12 months
  • Target

    OAS3 (2'-5' Oligoadenylate Synthetase 3 (OAS3))

    Andere Bezeichnung

    OAS3

    Hintergrund

    Synonyms: 2-5''oligoA synthase 3, 2 5' oligoA synthetase 3, 2 5'LIGO, 2 5A synthetase 3, 2''-5''-oligoadenylate synthase 3, 2-5A synthase 3, MGC133260, OAS3 2' 5' oligoadenylate synthetase 3, 100 kDa, OAS3, OAS3_HUMAN, p100, p100 OAS, p100OAS.

    Background: The 2'- 5'- oligoadenylate synthetase (OAS) family is comprised of four members: OAS1, OAS2, OAS3 and OASL. These proteins are induced by interferons and function to convert ATP into 2'- 5'- linked oligomers of adenosine in the presence of double-stranded RNA and magnesium ions. Copper, iron and zinc ions strongly inhibit the OAS enzymatic activity, while manganese ions can replace magnesium ions as an activator. The OAS family plays a significant role in the inhibition of cellular protein synthesis, apoptosis and growth, and its members are important factors in viral infection resistance. OAS3, also referred to as p100, contains three adjacent OAS1-like domains and maps to the human chromosome 12q24.2

    Gen-ID

    4940

    Pathways

    Hepatitis C
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