EED Antikörper (AA 51-150) (Cy5.5)

Produktnummer ABIN1706384

Produktdetails anti-EED Antikörper (Cy5.5)

Target: EED (Embryonic Ectoderm Development (EED))

Bindungsspezifität: AA 51-150

Reaktivität: Xenopus laevis, Killifish (Oryzias latipes), Xenopus tropicalis

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EED Antikörper ist konjugiert mit Cy5.5

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Killifish (Oryzias latipes), Xenopus laevis, Xenopus tropicalis

Homologie: Human,Mouse,Rat,Cow,Sheep,Pig,Horse,Chicken,Rabbit,Zebrafish

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human EED

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu EED

Target: EED (Embryonic Ectoderm Development (EED))

Andere Bezeichnung: EED (EED Produkte)

Hintergrund:

Synonyms: eed, EED protein, EED_HUMAN, Embryonic ectoderm development, Embryonic ectoderm development isoform a, Embryonic ECTODERM development protein homolog, hEED, OTTHUMP00000235483, OTTHUMP00000235484, OTTHUMP00000235485, Polycomb protein eed, WAIT 1, WAIT-1, WAIT1, WD protein associating with integrin cytoplasmic tails 1.

Background: The transcriptional repressing Polycomb-group (PcG) and transcriptional activating trithorax-group (trxG) genes of Drosophila are part of a cellular memory system responsible for the stable inheritance of gene activity. PcG proteins assemble into multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. EED (embryonic ectoderm development) is the human homolog of Eed, a murine PcG gene homologous to the Drosophila homeotic gene, extra sex combs. The human EED protein is 99. 5 % identical to the mouse EED protein and contains seven WD repeats, which are involved in protein-protein interactions. There are two human EED transcripts that contain a putative 407-nucleotide-long intron and give rise to two HEED protein isoforms, 535 and 494 amino acids in length. EED interacts in a highly specific manner, both in vitro and in vivo, with histone deacetylase (HDAC) proteins.

Gen-ID: 8726