NFKBIB Antikörper (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, beta) (pSer19) (Cy5)

Details for Product anti-NFKBIB Antibody No. ABIN1705035
Antigen
  • NFKBIB
  • IKB-beta
  • IKappaBbeta
  • IkB
  • IkBb
  • IKBB
  • TRIP9
  • NFKB inhibitor beta
  • nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta
  • NFKBIB
  • Nfkbib
Epitop
pSer19
56
21
19
11
10
7
7
4
3
3
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
239
132
110
10
8
8
7
5
4
1
1
1
Wirt
Kaninchen
207
34
Klonalität
Polyklonal
Konjugat
Dieser NFKBIB Antikörper ist konjugiert mit Cy5
10
8
8
8
8
8
7
4
4
2
2
2
2
2
2
2
2
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
143
85
85
31
27
26
11
7
5
3
1
Optionen
Immunogen KLH conjugated synthetic phosphopeptide derived from human NFKBIB around the phosphorylation site of Ser19
Isotyp IgG
Reinigung Purified by Protein A.
Plasmids, Primers & others Plasmide, Primers & weitere NFKBIB products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung Ikb beta (NFKBIB Antibody Abstract)
Hintergrund

The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jul 2011].

Synonyms: I kappa B beta, I-kappa-B-beta, IkappaBbeta, IKB beta, IkB-B, IkB-beta, IKBB, IKBB_HUMAN, IkBbeta, NF kappa BIB, NF-kappa-B inhibitor beta, NF-kappa-BIB, Nfkbib, Thyroid receptor interacting protein 9, Thyroid receptor-interacting protein 9, TR interacting protein 9, TR-interacting protein 9, TRIP-9, TRIP9.

Pathways NF-kappaB Signalweg, Activation of Innate immune Response, Maintenance of Protein Location, Toll-Like Receptors Cascades
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
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