PRICKLE1 Antikörper (Prickle Homolog 1 (Drosophila)) (Cy5)

Details for Product anti-PRICKLE1 Antibody No. ABIN1704986
Antigen
  • EPM1B
  • RILP
  • Rilp
  • 1110058P22Rik
  • AW215793
  • Prickle
  • mpk1
  • Prickle-b
  • XPk
  • prickle
  • prickle planar cell polarity protein 1
  • prickle planar cell polarity protein 1 S homeolog
  • PRICKLE1
  • Prickle1
  • prickle1.S
Reaktivität
Human, Maus, Ratte (Rattus)
42
21
19
Wirt
Kaninchen
40
2
Klonalität
Polyklonal
Konjugat
Dieser PRICKLE1 Antikörper ist konjugiert mit Cy5
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
30
24
12
4
4
2
1
1
1
Optionen
Immunogen KLH conjugated synthetic peptide derived from human Prickle
Isotyp IgG
Reinigung Purified by Protein A.
Plasmids, Primers & others Plasmide, Primers & weitere PRICKLE1 products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung Prickle (PRICKLE1 Antibody Abstract)
Hintergrund

Prickle1 is an 831 amino acid protein that contains one PET domain and three LIM zinc-binding domains and localizes to the cytoplasm, as well as to the nuclear membrane. Expressed at higher levels in placenta and at lower levels in liver, brain, kidney, lung and pancreas, Prickle1 is thought to function as a nuclear receptor that interacts with NRSF, a silencer protein that binds the DNA sequence element NRSE (neuron-restrictive silencer element). Defects in the gene encoding Prickle1 are associated with autosomal recessive progressive myoclonic epilepsy-1B, which is characterized by quick jerks of the arms, shoulders or legs. The gene encoding Prickle1 maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5 % of the human genome.

Synonyms: FLJ31627, FLJ31937, MGC138902, MGC138903, EPM1B, Prickle 1, Prickle homolog 1 Drosophila, Prickle like protein 1, Prickle-like 1, Prickle1, REST-Interacting LIM Domain Protein, REST/NRSF interacting LIM domain protein 1, RILP, PRIC1_HUMAN.

Gen-ID 144165
Pathways Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development, Protein targeting to Nucleus
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
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