Cardiac muscle myosin is a hexamer consisting of two heavy chain subunits, two light chain subunits, and two regulatory subunits. This gene encodes the alpha heavy chain subunit of cardiac myosin. The gene is located 4kb downstream of the gene encoding the beta heavy chain subunit of cardiac myosin. Mutations in this gene cause familial hypertrophic cardiomyopathy and atrial septal defect 3.
Synonyms: Alpha MHC, ASD3, CMD1S, CMH1, MGC138376, MGC138378, MPD1, MYH 6, MYH 7, MYH6, MYH7, MYHC A, MYHC, MYHC B, MyHC-alpha, MyHC-beta, MYHCA, MYHCB, Myosin heavy chain cardiac muscle alpha isoform, Myosin heavy chain cardiac muscle beta isoform, Myosin heavy polypeptide 7 cardiac muscle beta, MYH6_HUMAN, MYH7_HUMAN.