Hedgehog Acyltransferase-Like (HHATL) Antikörper (Cy5)

Details zu Produkt Nr. ABIN1704952
Antigen
  • Gup1
  • RGD1311911
  • gup1
  • oact3
  • mboat3
  • MGC53261
  • mstp002
  • MGC89797
  • GUP1
  • 1110011D13Rik
  • C3orf3
  • MBOAT3
  • MSTP002
  • OACT3
  • c3orf3a
  • gup1a
  • zgc:77750
  • hedgehog acyltransferase-like
  • hedgehog acyltransferase like S homeolog
  • hedgehog acyltransferase like
  • hedgehog acyltransferase like, a
  • Hhatl
  • hhatl.S
  • HHATL
  • hhatl
  • hhatla
Reaktivität
Human, Maus, Ratte (Rattus)
23
18
18
Wirt
Kaninchen
22
1
Klonalität
Polyklonal
Konjugat
Cy5
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
12
10
6
5
4
2
1
1
Optionen
Immunogen KLH conjugated synthetic peptide derived from human HHATL/GUP1
Isotyp IgG
Reinigung Purified by Protein A.
Antigen
Andere Bezeichnung Hhatl/Gup1 (HHATL Antibody Abstract)
Hintergrund

GUP1 is a 504 amino acid multipass membrane protein of the endoplasmic reticulum that functions as a membrane bound O-acyltransferase. With specific expression in heart, GUP1 negatively regulates amino-terminal palmitoylation of Shh by HHAT, a protein that is required for Shh signaling. Deletion of the gene encoding GUP1 results in higher sensibility to specific sphinogolipid biosynthesis inhibitors and resistance to ergosterol biosynthesis inhibitors, indicating that GUP1 is an essential component in lipid metabolism. Also, GUP1 also seems to be important for cell wall assembly and stability due to evidence in Saccharomyces cerevisiae GUP1 mutants, which exhibit altered plasma membrane lipid composition and membrane potential.

Synonyms: C3orf3, Glycerol uptake/transporter homolog, GUP1, GUP1 glycerol uptake/transporter homolog, Hedgehog acyltransferase like, Hedgehog acyltransferase-like protein, Hhatl, HHATL_HUMAN, KIAA1173, MBOAT3, Membrane bound O acyltransferase domain containing 3, MSTP002, OACT3, Protein-cysteine N-palmitoyltransferase HHAT-like protein.

Gen-ID 57467
Pathways Hedgehog Signalweg
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
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