FGFR3 Antikörper (Fibroblast Growth Factor Receptor 3) (pTyr724) (Cy5)

Details for Product anti-FGFR3 Antibody No. ABIN1704704
Antigen
  • FGFR3
  • LOC100034114
  • ACH
  • CD333
  • CEK2
  • HSFGFR3EX
  • JTK4
  • FR3
  • Fgfr-3
  • Flg-2
  • HBGFR
  • Mfr3
  • sam3
  • fc27h01
  • wu:fc27h01
  • fibroblast growth factor receptor 3
  • fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) S homeolog
  • FGFR3
  • fgfr3.S
  • Fgfr3
  • fgfr3
Epitop
pTyr724
23
13
12
11
10
9
9
9
8
7
7
4
4
4
4
3
3
2
2
2
2
2
2
1
1
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
174
79
65
6
3
3
3
1
Wirt
Kaninchen
168
12
1
Klonalität
Polyklonal
Konjugat
Dieser FGFR3 Antikörper ist konjugiert mit Cy5
15
10
8
6
6
6
6
6
5
4
4
4
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
112
81
78
20
13
12
6
4
4
4
2
1
1
1
1
Optionen
Immunogen KLH conjugated synthetic phosphopeptide derived from human FGFR3 around the phosphorylation site of Tyr724
Isotyp IgG
Reinigung Purified by Protein A.
Plasmids, Primers & others Plasmide, Primers & weitere FGFR3 products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung Fgfr3 (FGFR3 Antibody Abstract)
Hintergrund

The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used, adrenocorticotrophin, essential for normal steroidogenesis and the maintenance of normal adrenal weight, and lipotropin beta are the major end products. In other tissues, including the hypothalamus, placenta, and epithelium, all cleavage sites may be used, giving rise to peptides with roles in pain and energy homeostasis, melanocyte stimulation, and immune modulation. These include several distinct melanotropins, lipotropins, and endorphins that are contained within the adrenocorticotrophin and beta-lipotropin peptides. Mutations in this gene have been associated with early onset obesity, adrenal insufficiency, and red hair pigmentation. Alternatively spliced transcript variants encoding the same protein have been described.

Synonyms: FGFR3 phospho Y724, FGFR3 phospho Tyr724, p-FGFR3 phospho Y724, ACH, CD 333, CD333, CD333 antigen, CEK 2, CEK2, FGFR 3, Fibroblast growth factor receptor 3 achondroplasia thanatophoric dwarfism, Fibroblast growth factor receptor 3, Heparin binding growth factor receptor, HSFGFR3EX, Hydroxyaryl protein kinase, JTK 4, JTK4, MFR 3, SAM 3, Tyrosine kinase JTK 4, Tyrosine kinase JTK4, Z FGFR 3.

Gen-ID 2261
Pathways RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Stem Cell Maintenance, Growth Factor Binding
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
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