Embryonic Ectoderm Development (EED) Antikörper (Cy5)

Details zu Produkt Nr. ABIN1704426
Antigen
  • Xeed
  • heed
  • wait1
  • EED
  • HEED
  • WAIT1
  • zgc:112509
  • Xeed-B
  • eed
  • psXEED
  • ENSMUSG00000039373
  • l(7)5Rn
  • l7Rn5
  • lusk
  • Xeed-A
  • embryonic ectoderm development
  • embryonic ectoderm development S homeolog
  • microRNA 6755
  • embryonic ectoderm development L homeolog
  • eed
  • EED
  • eed.S
  • MIR6755
  • Eed
  • eed.L
Reaktivität
Human, Maus, Ratte (Rattus)
97
67
45
8
7
7
7
7
6
3
3
3
3
2
Wirt
Kaninchen
89
13
3
Klonalität
Polyklonal
Konjugat
Cy5
4
3
3
3
3
3
2
1
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
74
29
13
12
9
5
3
3
3
3
2
1
1
1
Optionen
Immunogen KLH conjugated synthetic peptide derived from human EED
Isotyp IgG
Reinigung Purified by Protein A.
Antigen
Andere Bezeichnung Eed (EED Antibody Abstract)
Hintergrund

The transcriptional repressing Polycomb-group (PcG) and transcriptional activating trithorax-group (trxG) genes of Drosophila are part of a cellular memory system responsible for the stable inheritance of gene activity. PcG proteins assemble into multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. EED (embryonic ectoderm development) is the human homolog of Eed, a murine PcG gene homologous to the Drosophila homeotic gene, extra sex combs. The human EED protein is 99. 5 % identical to the mouse EED protein and contains seven WD repeats, which are involved in protein-protein interactions. There are two human EED transcripts that contain a putative 407-nucleotide-long intron and give rise to two HEED protein isoforms, 535 and 494 amino acids in length. EED interacts in a highly specific manner, both in vitro and in vivo, with histone deacetylase (HDAC) proteins.

Synonyms: eed, EED protein, EED_HUMAN, Embryonic ectoderm development, Embryonic ectoderm development isoform a, Embryonic ECTODERM development protein homolog, hEED, OTTHUMP00000235483, OTTHUMP00000235484, OTTHUMP00000235485, Polycomb protein eed, WAIT 1, WAIT-1, WAIT1, WD protein associating with integrin cytoplasmic tails 1.

Gen-ID 8726
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
Haben Sie etwas anderes gesucht?