Integrin beta 2 Antikörper (ITGB2) (AA 724-769) (Cy5)

Details for Product anti-ITGB2 Antibody No. ABIN1704386
Antigen
  • CD18
  • LAD
  • LCAMB
  • LFA-1
  • MAC-1
  • MF17
  • MFI7
  • 2E6
  • AI528527
  • Cd18
  • Lfa1
  • ITGB2
  • itgb2
  • itgb2-a
  • itgb2-b
  • integrin subunit beta 2
  • integrin beta 2
  • integrin subunit beta 2 S homeolog
  • ITGB2
  • Itgb2
  • itgb2.S
Epitop
AA 724-769, pThr758
44
35
20
15
15
11
10
7
7
6
5
5
5
4
4
3
3
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
449
181
109
21
19
9
6
4
4
3
3
3
3
2
2
Wirt
Kaninchen
289
180
109
5
2
1
Klonalität
Polyklonal
Konjugat
Dieser Integrin beta 2 Antikörper ist konjugiert mit Cy5
76
62
45
21
12
8
8
6
5
5
5
5
4
3
3
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
356
247
156
132
86
59
57
51
42
38
13
9
9
7
6
1
1
1
1
Optionen
Immunogen KLH conjugated synstic phosphopeptide derived from human CD18 around the phosphorylation site of Thr758
Isotyp IgG
Reinigung Purified by Protein A.
Plasmids, Primers & others Plasmide, Primers & weitere Integrin beta 2 products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung CD18 (ITGB2 Antibody Abstract)
Hintergrund

Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrins alpha-M/beta-2 and alpha-X/beta-2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin alpha-X/beta-2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin alpha-M/beta-2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin alpha-M/beta-2 is also a receptor for factor X. Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1. Triggers neutrophil transmigration during lung injury through PTK2B/PYK2-mediated activation.

Subcellular location: Cytoplasm

Synonyms: LAD, CD18, MF17, MFI7, LCAMB, LFA-1, MAC-1, Integrin beta-2, Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta, Complement receptor C3 subunit beta, ITGB2

Gen-ID 3689
UniProt P05107
Pathways NF-kappaB Signalweg, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
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