Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

KIT Antikörper (pTyr568, pTyr570) (Cy5)

KIT Reaktivität: Human WB, FACS Wirt: Kaninchen Polyclonal Cy5
Produktnummer ABIN1704371
  • Target Alle KIT Antikörper anzeigen
    KIT (Mast/stem Cell Growth Factor Receptor (KIT))
    Bindungsspezifität
    • 33
    • 23
    • 23
    • 22
    • 19
    • 19
    • 16
    • 16
    • 16
    • 16
    • 16
    • 15
    • 12
    • 12
    • 11
    • 10
    • 10
    • 9
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 4
    • 4
    pTyr568, pTyr570
    Reaktivität
    • 585
    • 232
    • 63
    • 29
    • 27
    • 25
    • 16
    • 12
    • 5
    • 4
    • 2
    • 2
    • 1
    Human
    Wirt
    • 518
    • 100
    • 40
    • 2
    • 2
    • 1
    Kaninchen
    Klonalität
    • 511
    • 152
    • 1
    Polyklonal
    Konjugat
    • 228
    • 64
    • 60
    • 59
    • 46
    • 46
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser KIT Antikörper ist konjugiert mit Cy5
    Applikation
    • 355
    • 329
    • 279
    • 147
    • 91
    • 91
    • 66
    • 46
    • 44
    • 42
    • 34
    • 24
    • 10
    • 8
    • 6
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    Kreuzreaktivität
    Human
    Homologie
    Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic phosphopeptide derived from human c-Kit around the phosphorylation site of Tyr568 + Tyr570
    Isotyp
    IgG
    Top Product
    Discover our top product KIT Primärantikörper
  • Applikationshinweise
    FCM 1:20-100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    KIT (Mast/stem Cell Growth Factor Receptor (KIT))
    Andere Bezeichnung
    c-Kit + (KIT Produkte)
    Hintergrund

    Synonyms: c-Kit phospho Y568 + Y570, p-c-Kit phospho Y568 + Y570, C Kit, c-Kit, CD 117, CD117, CD117 antigen, KIT, KIT_HUMAN, Mast/stem cell growth factor receptor, Mast/stem cell growth factor receptor Kit, p145 c-kit, PBT, Piebald trait protein, Proto oncogene c Kit, Proto oncogene tyrosine protein kinase Kit, Proto-oncogene c-Kit, SCF Receptor, SCFR, soluble KIT variant 1, Stem cell factor receptor, tyrosine protein kinase Kit, Tyrosine-protein kinase Kit, v kit Hardy Zuckerman 4 feline sarcoma viral oncogene homolog, v kit Hardy Zuckerman 4 feline sarcoma viral oncogene like protein, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog.

    Background: c-Kit is a transmembrane tyrosine kinase encoded by the cKit proto oncogene. c-Kit acts to regulate a variety of biological responses including cell proliferation, apoptosis, chemotaxis and adhesion. Ligand binding to the extracellular domain leads to autophosphorylation on several tyrosine residues within the cytoplasmic domain, and activation. Mutations in c-Kit have been found to be important for tumor growth and progression in a variety of cancers including mast cell diseases, gastrointestinal stromal tumor, acute myeloid leukemia, Ewing sarcoma and lung cancer. Phosphorylation at tyrosine 721 of c-Kit allows binding and activation of PI3 kinase.

    Gen-ID
    3815
    Pathways
    RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Sensory Perception of Sound, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity
Sie sind hier:
Kundenservice