ANKK1 Antikörper (AA 101-200) (Cy5)

Produktnummer ABIN1704141

Dieser Anti-ANKK1 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von ANKK1 in WB, IF (cc) und IF (p). Geeignet für Maus und Ratte.

Kurzübersicht für ANKK1 Antikörper (AA 101-200) (Cy5) (ABIN1704141)

Target: ANKK1 (Ankyrin Repeat and Protein Kinase Domain-Containing Protein 1 (ANKK1))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ANKK1 Antikörper ist konjugiert mit Cy5

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-ANKK1 Antikörper (Cy5)

Bindungsspezifität: AA 101-200

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Dog,Horse,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ANKK1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu ANKK1

Target: ANKK1 (Ankyrin Repeat and Protein Kinase Domain-Containing Protein 1 (ANKK1))

Andere Bezeichnung: ANKK1

Hintergrund:

Synonyms: Ankyrin repeat and kinase domain containing 1, Ankyrin repeat and protein kinase domain containing protein 1, EC 2.7.11.1, PKK2, Protein kinase PKK2, SGK288, Sugen kinase 288, X kinase, ANKK1_HUMAN.

Background: The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. ANKK1 (ankyrin repeat and kinase domain containing 1), also known as PKK2 or SGK288, is a 765 amino acid protein that belongs to the Ser/Thr protein kinase family and contains 12 ANK repeats and one protein kinase domain. Highly expressed in brain tissue and present in lower amounts in placenta and spinal cord, ANKK1 functions to catalyze the ATP-dependent phosphorylation of target proteins and is thought to play a role in alcohol and nicotine dependence. The gene encoding ANKK1 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4 % of the human genome.

Gen-ID: 255239