ABL1 Antikörper (pTyr226) (Cy3)
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- Target Alle ABL1 Antikörper anzeigen
- ABL1 (C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1))
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Bindungsspezifität
- pTyr226
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ABL1 Antikörper ist konjugiert mit Cy3
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Applikation
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Spezifität
- This phosphorylation site is homologous to that of Tyr245 in c-ABL isoform IB.
- Kreuzreaktivität
- Human, Maus
- Homologie
- Rat,Dog,Pig,Horse,Chicken,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic phosphopeptide derived from human c-Abl isoform IA around the phosphorylation site of Tyr226
- Isotyp
- IgG
- Top Product
- Discover our top product ABL1 Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- ABL1 (C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1))
- Andere Bezeichnung
- c-ABL (ABL1 Produkte)
- Synonyme
- ABL antikoerper, JTK7 antikoerper, bcr/abl antikoerper, c-ABL antikoerper, p150 antikoerper, v-abl antikoerper, AI325092 antikoerper, Abl antikoerper, E430008G22Rik antikoerper, c-Abl antikoerper, ABL proto-oncogene 1, non-receptor tyrosine kinase antikoerper, c-abl oncogene 1, non-receptor tyrosine kinase antikoerper, Tyrosine-protein kinase abl-1 antikoerper, ABL1 antikoerper, Abl1 antikoerper, abl-1 antikoerper, abl1 antikoerper
- Hintergrund
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Synonyms: c-Ablphospho Tyr226, c-Ablphospho Tyr226, p-c-AblTyr226, Abelson Murine Leukemia Viral Oncogene Homolog 1, Abelson murine leukemia viral v abl oncogene homolog 1, Abl 1, ABL, Abl protein, Abl1, Bcr/c abl oncogene protein, JTK 7, JTK7, p150, Proto oncogene tyrosine protein kinase ABL1, Transformation gene oncogene ABL, v abl Abelson murine leukemia viral oncogene homolog 1, v abl, ABL1_HUMAN.
Background: The c Abl proto oncogene encodes a protein tyrosine kinase that is located in the cytoplasm and nucleus. In chronic myelogenous leukemia and in a subset of acute lymphoblastic leukemias, the c Abl proto oncogene undergoes a (9,22) chromosomal translocation producing a novel rearranged chromosome (the Philadelphia chromosome) As the result of the fusion of c Abl sequences from chromosome 9 to the Bcr gene on chromosome 22. The molecular consequence of this translocation is the generation of a chimeric Bcr/Abl mRNA encoding activated Abl protein tyrosine kinase.
- Gen-ID
- 25
- Pathways
- Apoptose, Regulation of Muscle Cell Differentiation, Platelet-derived growth Factor Receptor Signaling, Lipid Metabolism
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