FFAR1 Antikörper (AA 121-220) (Biotin)
Kurzübersicht für FFAR1 Antikörper (AA 121-220) (Biotin) (ABIN1701125)
Target
Alle FFAR1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
- 
    - 
                                            Bindungsspezifität
- AA 121-220
- 
                                            Kreuzreaktivität
- Human, Maus
- 
                                            Homologie
- Rat,Dog,Pig
- 
                                            Aufreinigung
- Purified by Protein A.
- 
                                            Immunogen
- KLH conjugated synthetic peptide derived from human GPR40
- 
                                            Isotyp
- IgG
 
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- 
    
- 
    - 
                                            Applikationshinweise
- 
                        WB 1:300-5000
 IHC-P 1:200-400
 IHC-F 1:100-500
- 
                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
- 
                                            
- 
    - 
                                            Format
- Liquid
- 
                                            Konzentration
- 1 μg/μL
- 
                                            Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 
                                            Konservierungsmittel
- ProClin
- 
                                            Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 
                                            Lagerung
- -20 °C
- 
                                            Informationen zur Lagerung
- Store at -20°C for 12 months.
- 
                                            Haltbarkeit
- 12 months
 
- 
                                            
- 
    - FFAR1 (Free Fatty Acid Receptor 1 (FFAR1))
- 
                                            Andere Bezeichnung
- GPR40
- 
                                            Hintergrund
- 
                        Synonyms: FFA1R, GPR40, GPCR40, Free fatty acid receptor 1, G-protein coupled receptor 40, FFAR1 Background: G-protein coupled receptor for medium and long chain saturated and unsaturated fatty acids that plays an important role in glucose homeostasis. Fatty acid binding increases glucose-stimulated insulin secretion, and may also enhance the secretion of glucagon-like peptide 1 (GLP-1). May also play a role in bone homeostasis, receptor signaling activates pathways that inhibit osteoclast differentiation (By similarity). Ligand binding leads to a conformation change that triggers signaling via G-proteins that activate phospholipase C, leading to an increase of the intracellular calcium concentration. Seems to act through a G(q) and G(i)-mediated pathway. 
- 
                                            Gen-ID
- 2864
- 
                                            UniProt
- O14842
- 
                                            Pathways
- Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Peptide Hormone Metabolism, Carbohydrate Homeostasis
 Target
- 
                    
 
                                     
                                     
                                    