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FFAR1 Antikörper (AA 121-220) (Biotin)

This anti-FFAR1 antibody (ABIN1701125) is a Rabbit Polyclonal antibody detecting FFAR1 in WB, ELISA, IHC (p), IHC (fro). Suitable for Human, Mouse.
Produktnummer ABIN1701125

Quick Overview for FFAR1 Antikörper (AA 121-220) (Biotin) (ABIN1701125)

Target

Alle FFAR1 Antikörper anzeigen
FFAR1 (Free Fatty Acid Receptor 1 (FFAR1))

Reaktivität

  • 57
  • 29
  • 18
  • 5
  • 5
  • 3
  • 1
Human, Maus

Wirt

  • 57
  • 2
  • 1
Kaninchen

Klonalität

  • 58
  • 2
Polyklonal

Konjugat

  • 26
  • 4
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser FFAR1 Antikörper ist konjugiert mit Biotin

Applikation

  • 46
  • 17
  • 13
  • 13
  • 10
  • 7
  • 7
  • 5
  • 4
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Bindungsspezifität

    • 14
    • 8
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 121-220

    Kreuzreaktivität

    Human, Maus

    Homologie

    Rat,Dog,Pig

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human GPR40

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C for 12 months.

    Haltbarkeit

    12 months
  • Target

    FFAR1 (Free Fatty Acid Receptor 1 (FFAR1))

    Andere Bezeichnung

    GPR40

    Hintergrund

    Synonyms: FFA1R, GPR40, GPCR40, Free fatty acid receptor 1, G-protein coupled receptor 40, FFAR1

    Background: G-protein coupled receptor for medium and long chain saturated and unsaturated fatty acids that plays an important role in glucose homeostasis. Fatty acid binding increases glucose-stimulated insulin secretion, and may also enhance the secretion of glucagon-like peptide 1 (GLP-1). May also play a role in bone homeostasis, receptor signaling activates pathways that inhibit osteoclast differentiation (By similarity). Ligand binding leads to a conformation change that triggers signaling via G-proteins that activate phospholipase C, leading to an increase of the intracellular calcium concentration. Seems to act through a G(q) and G(i)-mediated pathway.

    Gen-ID

    2864

    UniProt

    O14842

    Pathways

    Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Peptide Hormone Metabolism, Carbohydrate Homeostasis
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