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Leupaxin Antikörper (AA 251-350) (Biotin)

LPXN Reaktivität: Human WB, ELISA, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN1700354
  • Target Alle Leupaxin (LPXN) Antikörper anzeigen
    Leupaxin (LPXN)
    Bindungsspezifität
    • 14
    • 7
    • 6
    • 6
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 251-350
    Reaktivität
    • 46
    • 19
    • 11
    • 1
    Human
    Wirt
    • 45
    • 2
    Kaninchen
    Klonalität
    • 47
    Polyklonal
    Konjugat
    • 13
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Leupaxin Antikörper ist konjugiert mit Biotin
    Applikation
    • 35
    • 20
    • 13
    • 13
    • 5
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Homologie
    Human,Mouse,Rat,Dog,Pig,Horse
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Leupaxin
    Isotyp
    IgG
    Top Product
    Discover our top product LPXN Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    Leupaxin (LPXN)
    Andere Bezeichnung
    Leupaxin (LPXN Produkte)
    Synonyme
    LDPL antikoerper, 4933402K05Rik antikoerper, A530083L21Rik antikoerper, AV278559 antikoerper, MGC140379 antikoerper, leupaxin antikoerper, hypothetical protein antikoerper, Leupaxin antikoerper, LPXN antikoerper, Lpxn antikoerper, lpxn antikoerper, PAAG_03110 antikoerper, PGTG_11441 antikoerper
    Hintergrund

    Synonyms: LDLP, LDPL, LPXN, LPXN_HUMAN.

    Background: Leupaxin is a 386 amino acid cytoplasmic protein and member of the paxillin family. Leupaxin is highly expressed in lymphoid tissues such as spleen, lymph node, thymus and appendix, with low expression in bone marrow and fetal liver. Consisting of four leucine-rich LD-motifs at the N-terminus and four LIM domains at the C-terminus, leupaxin associates with a member of the focal adhesion kinase family, PYK2, in lymphoid cells. The leupaxin and PYK2 complex is involved in cell type-specific signaling in which it regulates signaling at sites of adhesion. Leupaxin is a substrate for tyrosine kinase in lymphoid cells and is suggested to participate in and be regulated by tyrosine kinase activity. Leupaxin may be a potential progression marker for a subset of prostate cancer and may act as a novel coactivator of the androgen receptor.

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