Acetyl-CoA Carboxylase alpha Antikörper (pSer1263) (Biotin)

Produktnummer ABIN1700092

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Acetyl-CoA Carboxylase alpha in ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Acetyl-CoA Carboxylase alpha Antikörper (pSer1263) (Biotin) (ABIN1700092)

Target: Acetyl-CoA Carboxylase alpha (ACACA)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Acetyl-CoA Carboxylase alpha Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Produktdetails anti-Acetyl-CoA Carboxylase alpha Antikörper (Biotin)

Bindungsspezifität: pSer1263

Homologie: Human

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human Acetyl Coenzyme A Carboxylase alpha around the phosphorylation site of Ser1263

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu Acetyl-CoA Carboxylase alpha

Target: Acetyl-CoA Carboxylase alpha (ACACA)

Andere Bezeichnung: Acetyl Coenzyme A Carboxylase alpha

Hintergrund:

Synonyms: Acetyl Coenzyme A Carboxylase alpha phospho S1263, p-Acetyl Coenzyme A Carboxylase alpha phospho S1263, ACAC, ACACA, ACACA, ACACA_HUMAN, ACC alpha, ACC, ACC-alpha, ACC1, ACC1, ACCA, acetyl CoA carboxylase 1, acetyl Coenzyme A, Acetyl Coenzyme A, Biotin carboxylase, Acetyl-Coenzyme A Carboxylase alpha.

Background: Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

Pathways: AMPK Signaling, Ribonucleoside Biosynthetic Process, Warburg Effekt