Growth Hormone 2 Antikörper (AA 121-217) (AbBy Fluor® 488)

Produktnummer ABIN1694552

This anti-Growth Hormone 2 antibody (ABIN1694552) is a Rabbit Polyclonal antibody detecting Growth Hormone 2 in WB, IF (cc), IF (p). Suitable for Human.

Kurzübersicht für Growth Hormone 2 Antikörper (AA 121-217) (AbBy Fluor® 488) (ABIN1694552)

Target: Growth Hormone 2 (GH2)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Growth Hormone 2 Antikörper ist konjugiert mit AbBy Fluor® 488

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-Growth Hormone 2 Antikörper (AbBy Fluor® 488)

Bindungsspezifität: AA 121-217

Homologie: Human

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GH2/Growth hormone 2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu Growth Hormone 2

Target: Growth Hormone 2 (GH2)

Andere Bezeichnung: GH2/Growth hormone 2

Hintergrund:

Synonyms: GH 2, GH V, GH2, GHL, GHV, Growth hormone 2, Growth hormone variant, hGH V, hGHV, Placenta specic growth hormone, Placental specic growth hormone, SOM2_HUMAN.

Background: Growth hormone 2 (GH2) is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation, an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Mutations in this gene lead to placental growth hormone/lactogen deficiency. The major role of GH2 in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues.

Gen-ID: 2689

Pathways: NF-kappaB Signalweg, JAK-STAT Signalweg, Response to Growth Hormone Stimulus