Telefon:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antikoerper-online.de

HHATL Antikörper (AA 25-125) (Alexa Fluor 350)

HHATL Reaktivität: Human IF (cc), IF (p) Wirt: Kaninchen Polyclonal Alexa Fluor 350
Produktnummer ABIN1694061
$438.15
Zzgl. Versandkosten $45.00
100 μL
Lieferung in 11 bis 16 Werktagen
  • Target Alle HHATL Antikörper anzeigen
    HHATL (Hedgehog Acyltransferase-Like (HHATL))
    Bindungsspezifität
    • 14
    • 3
    • 1
    AA 25-125
    Reaktivität
    • 18
    • 2
    • 2
    Human
    Wirt
    • 17
    • 1
    Kaninchen
    Klonalität
    • 17
    • 1
    Polyklonal
    Konjugat
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser HHATL Antikörper ist konjugiert mit Alexa Fluor 350
    Applikation
    • 12
    • 12
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human HHATL/GUP1
    Isotyp
    IgG
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C/-80 °C
    Informationen zur Lagerung
    Store at -20°C, for long storage, store at -80°C. Avoid multiple freeze-thaw cycles
    Haltbarkeit
    12 months
  • Target
    HHATL (Hedgehog Acyltransferase-Like (HHATL))
    Andere Bezeichnung
    HHATL/GUP1 (HHATL Produkte)
    Synonyme
    Gup1, RGD1311911, gup1, oact3, mboat3, MGC53261, mstp002, MGC89797, GUP1, 1110011D13Rik, C3orf3, MBOAT3, MSTP002, OACT3, c3orf3a, gup1a, zgc:77750, hedgehog acyltransferase-like, hedgehog acyltransferase like S homeolog, hedgehog acyltransferase like, hedgehog acyltransferase like, a, Hhatl, hhatl.S, HHATL, hhatl, hhatla
    Hintergrund

    GUP1 is a 504 amino acid multipass membrane protein of the endoplasmic reticulum that functions as a membrane bound O-acyltransferase. With specific expression in heart, GUP1 negatively regulates amino-terminal palmitoylation of Shh by HHAT, a protein that is required for Shh signaling. Deletion of the gene encoding GUP1 results in higher sensibility to specific sphinogolipid biosynthesis inhibitors and resistance to ergosterol biosynthesis inhibitors, indicating that GUP1 is an essential component in lipid metabolism. Also, GUP1 also seems to be important for cell wall assembly and stability due to evidence in Saccharomyces cerevisiae GUP1 mutants, which exhibit altered plasma membrane lipid composition and membrane potential.

    Subcellular location: Cytoplasm, Cell membrane

    Synonyms: C3orf3, Glycerol uptake/transporter homolog, GUP1, GUP1 glycerol uptake/transporter homolog, Hedgehog acyltransferase like, Hedgehog acyltransferase-like protein, Hhatl, HHATL_HUMAN, KIAA1173, MBOAT3, Membrane bound O acyltransferase domain containing 3, MSTP002, OACT3, Protein-cysteine N-palmitoyltransferase HHAT-like protein.

    Gen-ID
    57467
    Pathways
    Hedgehog Signalweg
Sie sind hier:
Kundenservice